Learning Hub

iPROLEPSIS project news Dec 23, 2025 Seasons Greetings from iPROLEPSIS Happy holidays and best wishes for the year ahead! READ MORE Nov 25, 2025 iPROLEPSIS Showcased at MEDICA 2025 Project presented by PLUX at an international medical technology trade fair READ MORE Nov 6, 2025 iPROLEPSIS Newsletter No. 10 Latest News from iPROLEPSIS READ MORE Oct 29, 2025 World Psoriasis Day 2025: Advancing Prevention and Care On World Psoriasis Day, iPROLEPSIS highlights ongoing efforts to improve early detection, prevention, and digital support for people living with psoriasis and psoriatic arthritis READ MORE Oct 2, 2025 iPROLEPSIS at the European Researchers’ Night 2025 Presentation of the iPROLEPSIS Games in Oeiras, Portugal by FMH/IST-ULisboa researchers READ MORE Jul 18, 2025 iPROLEPSIS at GRAPPA 2025: Advancing Digital Tools for Psoriatic Arthritis Care Exploring how digital biomarkers can support hand function assessment in real-world settings READ MORE Jun 27, 2025 iPROLEPSIS Games Presented at HiTech Program in Lisbon FMH/IST-ULisboa team showcased the project’s serious games to investors and health innovation experts READ MORE Dec 12, 2025 iPROLEPSIS 7th Plenary Meeting in Lisbon Partners met to review progress and next steps READ MORE Nov 24, 2025 iPROLEPSIS Games Showcased at Lisboa Games Week 2025 The FMH/IST-ULisboa team presented the iPROLEPSIS Games, connecting with the gaming community and industry stakeholders READ MORE Nov 3, 2025 iPROLEPSIS at IEEE HealthCom 2025: AI-Enabled Digital Health for Psoriatic Arthritis Project researchers presented new studies, co-chaired a workshop, and joined a panel on digital innovation in healthcare in Abu Dhabi READ MORE Oct 14, 2025 The iPROLEPSIS Learning Hub Has Been Renewed A refreshed space to learn more about psoriatic arthritis READ MORE Sep 11, 2025 Digital Innovation for Psoriatic Arthritis Prevention An interview with iPROLEPSIS coordinators in Thessalonikeon Polis on how digital tools, wearables, and AI can help prevent psoriatic arthritis READ MORE Jul 17, 2025 iPROLEPSIS, AI-PROGNOSIS & REBECCA: A Thematic Cluster on AI-Driven Digital Health Three EU-funded projects exploring real-world data, wearables, and personalised care in healthcare innovation READ MORE Jun 5, 2025 iPROLEPSIS Presented at EIT Health Morning Health Talk in Athens Co-Creating Health Innovation Ecosystems: Empowering Providers and Citizens Beyond Financial Incentives READ MORE Dec 4, 2025 iPROLEPSIS at Faculdade de Motricidade Humana PhD Seminar Lecture on recent findings shared with PhD students READ MORE Nov 6, 2025 iPROLEPSIS at IEEE-EMBS BSN 2025 Showcasing iPROLEPSIS at a leading international conference on body sensor research READ MORE Oct 29, 2025 World Psoriasis Day: iPROLEPSIS featured by HaDEA On World Psoriasis Day, the European Health and Digital Executive Agency (HaDEA) highlights how the iPROLEPSIS project is advancing early detection and personalised care for psoriatic arthritis READ MORE Oct 8, 2025 iPROLEPSIS presented at the MULTIPULM project kick-off meeting iPROLEPSIS tools to be adapted for clinical studies in Brazil, Serbia, and Türkiye READ MORE Jul 24, 2025 iPROLEPSIS Games Pitch video from HiTech 2025 iPROLEPSIS Games presented during the HiSeedTech programme READ MORE Jul 2, 2025 iPROLEPSIS Newsletter No. 9 Latest News from iPROLEPSIS READ MORE 1 2 3 ... 6 1 ... 1 2 3 4 5 6 ... 6

Learning Hub Explore resources to help you understand and manage psoriatic arthritis. Learning hub Key Facts Handbook News Feed Quizzes Search How is psoriatic arthritis treated? Non-pharmacological treatments See related Handbook section PREVIOUS NEXT

< BACK iPROLEPSIS Games Presented at the Pitch Competition during PhD Open Days Nov 7, 2024 Showcasing iPROLEPSIS Games at the PhD Open Days Pitch Competition On November 5th, Bárbara Ramalho from FMH/IST-ULisboa had the opportunity to present the iPROLEPSIS Games at the Pitch Competition during the PhD Open Days event at the Técnico Innovation Center . In her pitch, Bárbara highlighted the role of serious games in the iPROLEPSIS project, which aims to improve the care and management of psoriatic arthritis (PsA) through a personalised, game-based digital ecosystem. The PhD Open Days gave over a thousand students the chance to connect, network, and showcase their research to the academic community, industry professionals, and alumni. The Pitch Competition was a great opportunity for researchers to present their work and meet potential collaborators. 1/5 PREVIOUS NEXT

< BACK Psoriatic Arthritis Awareness Day Sep 28, 2023 iPROLEPSIS project is joining to celebrate the Psoriatic Arthritis Awareness Day This September 28th, the iPROLEPSIS project is joining to celebrate Psoriatic Arthritis Awareness Day, dedicated to raising awareness of the painful inflammatory disease often linked with psoriasis. iPROLEPSIS is a research and innovation initiative. The project uses cutting-edge technology and AI to develop a novel personalised digital care ecosystem for people with Psoriatic Arthritis. Join us on September 28th and help reshape the future of Psoriatic Arthritis care! News & Events iPROLEPSIS - events.png News & Events iPROLEPSIS - events.png 1/1 PREVIOUS NEXT

< BACK State-of-the-art analysis and datasets landscape Nov 6, 2023 Initial review, focusing on the state-of-the-art literature and existing datasets in the field of PsA Psoriatic arthritis is a chronic immune-mediated inflammatory arthritis occurring in patients with PsO. The disease manifestation can be heterogeneous between subjects, and the resulting musculoskeletal impairment can interfere with physical function as well as the quality of life of patients. In a collaborative effort, the iPROLEPSIS partners completed an initial extensive review, focusing on the state-of-the-art literature and existing datasets in the field of PsA, with a special focus on flare dynamics. The primary goal was to enhance the understanding of PsA by investigating disease symptoms, factors associated with flares, and markers for disease development and monitoring. The insights gained from the literature will provide background for various aspects of iPROLEPSIS research, such as investigating PsA inflammation drivers and monitoring, developing the iPROLEPSIS digital health ecosystem for personalised preventive care, and conducting clinical studies. Moreover, various multi-source datasets have been identified that can potentially yield valuable information for the discovery of PsA inflammation drivers and the development of novel digital biomarkers and predictive models for disease monitoring and progression prognosis. The identified datasets will be assessed for relevancy and usability, retrieved, harmonised and curated. These datasets and predictive models will contribute to the research on PsA monitoring and inflammation drivers. In addition, the identified existing datasets will also guide the development of the Lifestyle AI-driven recommendation system and the Serious Games. The key takeaways are: Fatigue, pain and stiffness are commonly reported symptoms in PsA Flare may be triggered by alterations in mood, stress, sleep, bowel movements, and environmental factors Flare may affect mood, stress, sleep, bowel movements, physical activity and fine motor skills Certain symptoms of PsA may also trigger or be triggered by flare Clinical measurements of PsA symptoms and hypothesized flare associated factors, mainly include questionnaires The use of smartphone and wearables to monitor physical activity (mainly through accelerometer data), fine motor skills (through keystroke dynamics), heart rate, heart rate variability have also shown potential to measure PsA symptoms and hypothesized flare associated factors Electrography techniques can also be used in the assessment of certain symptoms and flare associated factors Genetic factors may contribute to development of PsA, pain perception and response to treatment. Gut microbiome may be involved in PsA. MCs in skin are suggested to play a role in skin inflammation Monitoring of PsA can be achieved through clinical examination for inflamed joints, enthesitis dactylitis, nail and skin and subsequent calculation of relative indices and composite scores Imaging-based approaches including images obtained from smartphones and optoacoustics represent a complementary or alternative approach to clinical assessment Data-driven models can serve to find predictive relations even when the underlying mechanisms are poorly understood or are too complex. Recommendations and SGs present a potential approach to modify and improve diet and physical activity Besides diet and physical activity, SGs can also address other aspects of disease, including medication adherence, social support, cognition, breathing, biological and neural function OMOP CDM was opted to be used for standardising the datasets Future steps include an update on state-of-the-art literature and measurement tools on the topics covered by initial research and the identification of new datasets that could be relevant for data-driven models. News & Events iPROLEPSIS - news.png News & Events iPROLEPSIS - news.png 1/1 PREVIOUS NEXT

Learning Hub Explore resources to help you understand and manage psoriatic arthritis. Learning hub Key Facts Handbook News Feed Quizzes Search How will psoriatic arthritis affect me? Relationships and Family Planning See related Handbook section PREVIOUS NEXT

Learning Hub Explore resources to help you understand and manage psoriatic arthritis. Learning hub Key Facts Handbook News Feed Quizzes Search What causes psoriatic arthritis? See related Handbook section PREVIOUS NEXT

< BACK iPROLEPSIS at IEEE-EMBS BSN 2025 Nov 6, 2025 Showcasing iPROLEPSIS at a leading international conference on body sensor research The IEEE-EMBS International Conference on Body Sensor Networks (IEEE-EMBS BSN 2025) took place in Los Angeles, USA, from 3–5 November 2025. The conference brings together researchers, clinicians, and industry representatives working on body sensor technologies and their applications in health and biomedical research. iPROLEPSIS was showcased at the event by project partner PLUX , which hosted a dedicated booth. The project was presented to an international audience, increasing its visibility within the body sensor and digital health research community. IEEE EMBS 2025 2.HEIC IEEE EMBS 2025 1.HEIC IEEE EMBS 2025 3.HEIC IEEE EMBS 2025 2.HEIC 1/3 PREVIOUS NEXT

Learning how to live with psoriatic arthritis might feel like a challenge. But understanding your diagnosis can help you take control of your health. Learning Hub Explore resources to help you understand and manage psoriatic arthritis. Learning hub Key Facts Handbook News Feed Quizzes Search Psoriatic Arthritis Key Facts Key Facts Quizzes about Psoriatic Arthritis Take a Quiz Search about Psoriatic Arthritis Search Psoriatic Arthritis Handbook Handbook News Feed about Psoriatic Arthritis News Feed

The iPROLEPSIS project is where psoriatic arthritis inflammation is explained through multi-source data analysis guiding a novel personalized digital care ecosystem. iPROLEPSIS is a s olution for psoriatic arthritis The iPROLEPSIS project is where psoriatic arthritis inflammation is explained through multi-source data analysis guiding a novel personalised digital care ecosystem. ABOUT CONSORTIUM CONTACT US January 2026 TODAY Mon Tue Wed Thu Fri Sat Sun 29 30 31 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 1 2 3 4 5 6 7 8 Upcoming events Psoriatic Arthritis (PsA) is a chronic progressive inflammatory disease affecting 1-2% of the general population, while manifesting in up to 30% of people with psoriasis (PsO). Project vision and impact iPROLEPSIS is a Horizon Europe-funded project developing a novel personalised digital care ecosystem for people with PsA. The goal of iPROLEPSIS is to propose a novel ecosystem that involves Real World Data (RWD) collection mechanisms and a powerful decision support system to provide new knowledge for the key actionable factors that affect the health-to-PsA transition, adopting a multiscale/ multifactorial approach, so, with the use of xAI-based models, to offer an efficient, effective, and clinically validated personalised digital care ecosystem for PsA patients. DISCOVER MORE Project objectives and work packages iPROLEPSIS consortium works on 7 ambitious key objectives in the field of Psoriatic Arthritis (PsA) and has 6 Work Packages of the project that will bring together various and complementary expertise from consortium partners. DISCOVER MORE About project 15 Partners 9 Countries 48 m Project duration € 6,4M Total budget The core activity domains Establishment • The foundation for the project’s research activities is laid by means of an extensive exploration of the available literature and data and the design of the clinical data collection and validation studies; • Participatory design supporting the development of a user-oriented ecosystem of solutions will be employed to establish a framework for trustworthy AI-based R&D. Validation • The design and implementation of the clinical studies that will collect research data, validate the inflammatory symptoms digital biomarkers in individuals at risk of PsA and PSO patients, and evaluate the efficacy of the digital care tools with respect to prevention of inflammation exacerbation. Research and development • Research on multimodal data to reveal key PsA inflammation drivers, provide digital biomarkers of PsA inflammatory symptoms, and explore the effect of PsA on the joints and skin microvasculature, as well as the role of mast cells in PsA transition; • Synthesise the outcomes into a multiscale/multifactorial model of the health-to-PsA transition; • Deliver the integrated iPROLEPSIS digital health ecosystem comprising tools for personalised preventive PsA care, to empower patients and HCPs. Learning Hub Explore resources to help you understand and manage psoriatic arthritis. Handbook Handbook 2 Psoriatic Arthritis Key Facts Key Facts Psoriatic Arthritis Handbook Handbook Quizzes about Psoriatic Arthritis Take a Quiz Project news Handbook Handbook 2 iPROLEPSIS Showcased at MEDICA 2025 Read More iPROLEPSIS at IEEE-EMBS BSN 2025 Read More Seasons Greetings from iPROLEPSIS Read More DISCOVER MORE Contact us We welcome your comments or questions about iPROLEPSIS project! CONTACT US

< BACK Calling for Influencers: Join iPROLEPSIS as an Ambassador for Psoriatic Arthritis Feb 27, 2024 Join the iPROLEPSIS Initiative: Become an Ambassador for the iPROLEPSIS Project Join the iPROLEPSIS initiative! Calling all influencers, psoriatic arthritis warriors and health advocates to become iPROLEPSIS Ambassadors ! Our mission is to shed light upon the health-to-PsA transition through groundbreaking AI-driven analysis and cutting-edge technology. We are creating a digital health ecosystem for personalised psoriatic arthritis risk prediction and management. Are you passionate about health advocacy and psoriatic arthritis awareness? Become an iPROLEPSIS Ambassador and be a part of the change! Here is how you can make a difference as an iPROLEPSIS Ambassador: Promote the iPROLEPSIS mission Share iPROLEPSIS updates and developments Share personal stories and insights Ready to be a part of the change? Contact us at info@iprolepsis.eu , and we will provide you with more details. * Please note that this is voluntary, and no monetary compensation is offered. AI-PROGNOSIS events (8).png AI-PROGNOSIS events (8).png 1/1 PREVIOUS NEXT

Learning Hub Explore resources to help you understand and manage psoriatic arthritis. Learning hub Key Facts Handbook News Feed Quizzes Search How will psoriatic arthritis affect me? Work See related Handbook section PREVIOUS NEXT