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< BACK iPROLEPSIS at the Aristotle Innovation Forum 2026 May 27, 2026 Showcasing digital health tools for psoriatic arthritis care iPROLEPSIS participated in the Aristotle Innovation Forum 2026 , held in Thessaloniki, Greece, from 18–22 May 2026. This year's Forum, themed "Aristotle Meets AI", focused on innovation, technology, and artificial intelligence, bringing together the academic community and the general public. The iPROLEPSIS team from the Signal Processing & Biomedical Technology Unit – AUTH represented the project at the event, showcasing the iPROLEPSIS digital health ecosystem . Visitors had the opportunity for hands-on experience with our tools, designed to support better psoriatic arthritis care. The Forum offered an important opportunity to present iPROLEPSIS to both academic and general audiences. Image6.jpg Image2.jpg Image3.jpg Image6.jpg 1/4 PREVIOUS NEXT

iPROLEPSIS project news May 27, 2026 iPROLEPSIS at the Aristotle Innovation Forum 2026 Showcasing digital health tools for psoriatic arthritis care READ MORE Apr 22, 2026 iPROLEPSIS presented at TeraMed Conference 2026 in Angola The project and the iPROLEPSIS Games were presented, highlighting their relevance for digital health innovation READ MORE Mar 10, 2026 iPROLEPSIS Newsletter No. 11 Latest News from iPROLEPSIS READ MORE Feb 4, 2026 Designing Exergames for Psoriatic Arthritis: The Spy and Zen Forest Paradigms New iPROLEPSIS publication presents the co-design of exergames to support physical activity and rehabilitation in psoriatic arthritis READ MORE Dec 12, 2025 iPROLEPSIS 7th Plenary Meeting in Lisbon Partners met to review progress and next steps READ MORE Nov 24, 2025 iPROLEPSIS Games Showcased at Lisboa Games Week 2025 The FMH/IST-ULisboa team presented the iPROLEPSIS Games, connecting with the gaming community and industry stakeholders READ MORE Nov 3, 2025 iPROLEPSIS at IEEE HealthCom 2025: AI-Enabled Digital Health for Psoriatic Arthritis Project researchers presented new studies, co-chaired a workshop, and joined a panel on digital innovation in healthcare in Abu Dhabi READ MORE May 18, 2026 Transforming Psoriatic Disease Care Through Innovation and Real-World Data: GRAPPA 2025 Soapbox Highlights The article highlights how iPROLEPSIS uses digital tools, smartphone-based data and explainable AI to support personalised psoriatic arthritis monitoring READ MORE Apr 1, 2026 iPROLEPSIS at Healthcare & Medical Equipment Korea 2026 Presenting iPROLEPSIS at Korea’s leading medical technology exhibition READ MORE Mar 3, 2026 AI-Driven Early Prediction and Personalised Care | iPROLEPSIS, AI-PROGNOSIS & REBECCA A joint video highlighting how digital biomarkers and real-world data support patient-centred healthcare across three disease areas READ MORE Feb 3, 2026 Co-Designing Mobile Serious Games to Support Patients With Psoriatic Arthritis and Chronic Pain: Mixed Methods Study New peer-reviewed publication from iPROLEPSIS READ MORE Dec 4, 2025 iPROLEPSIS at Faculdade de Motricidade Humana PhD Seminar Lecture on recent findings shared with PhD students READ MORE Nov 6, 2025 iPROLEPSIS at IEEE-EMBS BSN 2025 Showcasing iPROLEPSIS at a leading international conference on body sensor research READ MORE Oct 29, 2025 World Psoriasis Day: iPROLEPSIS featured by HaDEA On World Psoriasis Day, the European Health and Digital Executive Agency (HaDEA) highlights how the iPROLEPSIS project is advancing early detection and personalised care for psoriatic arthritis READ MORE Apr 23, 2026 iPROLEPSIS presented at the European OHDSI Symposium 2026 A poster presented in Rotterdam highlighted cross-country harmonization of psoriatic arthritis cohorts into the OMOP Common Data Model READ MORE Mar 16, 2026 iPROLEPSIS at BIOSTEC 2026 Presenting iPROLEPSIS at an international forum on biomedical engineering and health technology READ MORE Feb 5, 2026 Modeling Interphalangeal Joints for Swelling Assessment in Psoriatic Arthritis via Smartphone Photographs New iPROLEPSIS publication presents a smartphone-based approach for remote joint swelling assessment in psoriatic arthritis READ MORE Dec 23, 2025 Seasons Greetings from iPROLEPSIS Happy holidays and best wishes for the year ahead! READ MORE Nov 25, 2025 iPROLEPSIS Showcased at MEDICA 2025 Project presented by PLUX at an international medical technology trade fair READ MORE Nov 6, 2025 iPROLEPSIS Newsletter No. 10 Latest News from iPROLEPSIS READ MORE 1 2 3 ... 6 1 ... 1 2 3 4 5 6 ... 6

The iPROLEPSIS project is where psoriatic arthritis inflammation is explained through multi-source data analysis guiding a novel personalized digital care ecosystem. iPROLEPSIS is a s olution for psoriatic arthritis The iPROLEPSIS project is where psoriatic arthritis inflammation is explained through multi-source data analysis guiding a novel personalised digital care ecosystem. ABOUT CONSORTIUM CONTACT US May 2026 TODAY Mon Tue Wed Thu Fri Sat Sun 27 28 29 30 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 1 2 3 Day (1/3) 60th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI) 4 Day (2/3) 60th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI) 5 Day (3/3) 60th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI) 6 7 Upcoming events Psoriatic Arthritis (PsA) is a chronic progressive inflammatory disease affecting 1-2% of the general population, while manifesting in up to 30% of people with psoriasis (PsO). Project vision and impact iPROLEPSIS is a Horizon Europe-funded project developing a novel personalised digital care ecosystem for people with PsA. The goal of iPROLEPSIS is to propose a novel ecosystem that involves Real World Data (RWD) collection mechanisms and a powerful decision support system to provide new knowledge for the key actionable factors that affect the health-to-PsA transition, adopting a multiscale/ multifactorial approach, so, with the use of xAI-based models, to offer an efficient, effective, and clinically validated personalised digital care ecosystem for PsA patients. DISCOVER MORE Project objectives and work packages iPROLEPSIS consortium works on 7 ambitious key objectives in the field of Psoriatic Arthritis (PsA) and has 6 Work Packages of the project that will bring together various and complementary expertise from consortium partners. DISCOVER MORE About project 15 Partners 9 Countries 48 m Project duration € 6,4M Total budget The core activity domains Establishment • The foundation for the project’s research activities is laid by means of an extensive exploration of the available literature and data and the design of the clinical data collection and validation studies; • Participatory design supporting the development of a user-oriented ecosystem of solutions will be employed to establish a framework for trustworthy AI-based R&D. Validation • The design and implementation of the clinical studies that will collect research data, validate the inflammatory symptoms digital biomarkers in individuals at risk of PsA and PSO patients, and evaluate the efficacy of the digital care tools with respect to prevention of inflammation exacerbation. Research and development • Research on multimodal data to reveal key PsA inflammation drivers, provide digital biomarkers of PsA inflammatory symptoms, and explore the effect of PsA on the joints and skin microvasculature, as well as the role of mast cells in PsA transition; • Synthesise the outcomes into a multiscale/multifactorial model of the health-to-PsA transition; • Deliver the integrated iPROLEPSIS digital health ecosystem comprising tools for personalised preventive PsA care, to empower patients and HCPs. Learning Hub Explore resources to help you understand and manage psoriatic arthritis. Handbook Handbook 2 Psoriatic Arthritis Key Facts Key Facts Psoriatic Arthritis Handbook Handbook Quizzes about Psoriatic Arthritis Take a Quiz Project news Handbook Handbook 2 iPROLEPSIS at the Aristotle Innovation Forum 2026 Read More Transforming Psoriatic Disease Care Through Innovation and Real-World Data: GRAPPA 2025 Soapbox Highlights Read More iPROLEPSIS presented at the European OHDSI Symposium 2026 Read More DISCOVER MORE Contact us We welcome your comments or questions about iPROLEPSIS project! CONTACT US

< BACK iPROLEPSIS, AI-PROGNOSIS & REBECCA: A Thematic Cluster on AI-Driven Digital Health Jul 17, 2025 Three EU-funded projects exploring real-world data, wearables, and personalised care in healthcare innovation Have you ever asked yourself how to make AI really effective along the patient journey? That was one of the first questions we asked ourselves when we launched our project. Along the way, we discovered we weren’t alone – many other research initiatives working with AI in healthcare were asking the same thing. That’s why we decided to take a step forward and create a cluster : a concrete way to collaborate, foster the impact of our solutions, and improve them through scientific exchange and an open science approach. AI-PROGNOSIS, iPROLEPSIS, and REBECCA – three EU-funded projects to advance patient-centric AI in healthcare. Focusing on Parkinson’s disease (PD), AI-PROGNOSIS is developing a suite of AI-powered tools for both patients and clinicians . These include early risk assessment, symptom monitoring, and medication support – based on real-world data from wearables and patient self-reports. It’s about enabling timely, data-driven decisions and bringing predictive analytics to the heart of primary care. iPROLEPSIS is building a comprehensive digital health ecosystem for psoriatic arthritis (PsA). It brings together a multisource biobank, a smartphone-based app powered by digital biomarkers and AI-driven predictive models, and an intervention module featuring therapeutic games, lifestyle coaching, and sleep support. The goal? To reshape the way we monitor and treat chronic inflammatory diseases through personalised mobile health solutions. Finally, REBECCA is working to improve long-term care for breast cancer survivors. By combining electronic health records with data from wearables and behaviour tracking , it generates real-world evidence on patients’ emotional, functional, and quality-of-life needs. Its explainable AI platform also supports caregivers and families via a dedicated app, empowering a more holistic approach to survivorship. What will we do together? We aim to contribute to the discussion on how AI-based digital health can support medical decision-making and real-time monitoring within daily hospital routines. I ntegrating AI into clinical practice is no easy task. Our solutions are designed to enable real-time health monitoring, informed decision-making, and disease management by leveraging biometric, behavioral, and clinical data –maximizing the impact along the patient journey. Another area of strong interest is the development of digital infrastructures that integrate wearable, clinical, behavioral, and environmental datasets. We believe these can be analyzed collectively through AI to generate real-world evidence and support both predictive and causal modeling – helping to guide research and inform treatment planning in more meaningful ways. Cluster.png Cluster.png 1/1 PREVIOUS NEXT

< BACK iPROLEPSIS Newsletter No. 9 Jul 2, 2025 Latest News from iPROLEPSIS Welcome to the ninth edition of the iPROLEPSIS newsletter, where we share the latest updates and progress from the project. iPROLEPSIS project newsletter_Issue No. 9_July 2025 .pdf Download PDF • 3.75MB iPROLEPSIS_newsletter cover.png iPROLEPSIS_newsletter cover.png 1/1 PREVIOUS NEXT

iPROLEPSIS project newsletter Mar 10, 2026 Issue No. 11 iPROLEPSIS project newsletter No 11 Welcome! This is the 11th edition of the iPROLEPSIS newsletter, where we share the latest updates and progress from the project. READ THE NEWSLETTER Nov 6, 2025 Issue No. 10 iPROLEPSIS project newsletter No 10 Welcome! This is the 10th edition of the iPROLEPSIS newsletter, where we share the latest updates and progress from the project. READ THE NEWSLETTER Jul 1, 2025 Issue No. 9 iPROLEPSIS project newsletter No 9 Welcome! This is the 9th edition of the iPROLEPSIS newsletter, where we share the latest updates and progress from the project. READ THE NEWSLETTER Apr 28, 2025 Issue No. 8 iPROLEPSIS project newsletter No 8 Welcome! This is the 8th edition of the iPROLEPSIS newsletter, where we share the latest updates and progress from the project. READ THE NEWSLETTER Jan 28, 2025 Issue No. 7 iPROLEPSIS project newsletter No 7 Welcome! This is the 7th edition of the Newsletter series of the iPROLEPSIS project. In this issue, we highlight the insights on the future of digital biomarkers in rheumatology care, offer key information about PsA and practical advice to improve daily life, update about past events. READ THE NEWSLETTER Oct 9, 2024 Issue No. 6 iPROLEPSIS project newsletter No 6 Welcome! This is the 6th edition of the Newsletter series of the iPROLEPSIS project. In this issue, we highlight the release of the miPROLEPSIS and miPROLEPSIS Joint Landmarker apps, recent publications, reflections on Psoriatic Arthritis Awareness Day and Psoriasis Awareness Month, and key takeaways from recent events. READ THE NEWSLETTER Jul 9, 2024 Issue No. 5 iPROLEPSIS project newsletter No 5 Welcome! This is the 5th edition of the Newsletter series of the iPROLEPSIS project. In this newsletter issue, we delve into the updates and progress of the project activities, synergies and events. READ THE NEWSLETTER Mar 7, 2024 Issue No. 4 iPROLEPSIS project newsletter No 4 Welcome! This is the 4th edition of the Newsletter series of the iPROLEPSIS project. Let's explore the latest developments and advancements in our project activities, collaborations, and upcoming events. READ THE NEWSLETTER Nov 30, 2023 Issue No. 3 iPROLEPSIS project newsletter No 3 Welcome! This is the 3rd edition of the Newsletter series of the iPROLEPSIS project. In this newsletter issue, we delve into the updates and progress of the project activities, synergies and events. READ THE NEWSLETTER Sep 5, 2023 Issue No. 2 iPROLEPSIS project newsletter No 2 Welcome! This is the 2nd edition of the Newsletter series of the iPROLEPSIS project. In this newsletter issue, we delve into the transformative power of user research and co-creation in the healthcare innovation research process. READ THE NEWSLETTER Jul 3, 2023 Issue No. 1 iPROLEPSIS project newsletter No 1 Welcome! This is the 1st edition of the newsletter series of the iPROLEPSIS project! The 1st newsletter informs you about the iPROLEPSIS project, its vision, pillars and objectives, and the partners involved. READ THE NEWSLETTER

< BACK iPROLEPSIS Project Presented at HUMAN Lab Meetup Jul 15, 2024 Enhancing Learning Through Innovative Serious Games and Digital Interventions On 8 July 2024, the HUMAN Lab meetup was organised by Universidade de Lisboa (Instituto Superior Técnico, IST). During the event, Bárbara Ramalho and Hugo Escobar from FMH/IST-ULisboa presented the iPROLEPSIS project and the iPROLEPSIS Games. They discussed the project's main goals, motivations, and key milestones, providing insights into their roles in the design and development of serious games. The presentation also addressed the expected outcomes of the project, emphasising how these innovative tools are designed to enhance learning experiences and offer effective digital interventions. 1/3 PREVIOUS NEXT

< BACK Empowering Girls in Tech: Celebrating GirlSteam 2024 Apr 25, 2024 Inspiring the Next Generation of Women in Information and Communication Technologies On 24th April, we celebrated International Girls in Information and Communication Technology Day – GirlSteam 2024, which is part of the larger initiative, International Girls in ICT Day (Girls in ICT 2024). This annual occasion is an international effort promoted by the United Nations agency ITU (International Telecommunication Union). During this event, Bárbara Ramalho (PhD student from FMH-ULisboa) presented the iPROLEPSIS project and the iPROLEPSIS Games . The primary aim was to raise awareness and encourage girls and young women to explore studies and careers in Information and Communication Technologies, especially in the field of Serious Games. iPROLEPSIS games 2.jpeg iPROLEPSIS games 1.jpeg Event banner.jpeg iPROLEPSIS games 2.jpeg 1/3 PREVIOUS NEXT

< BACK Maximising Project Impact: iPROLEPSIS Exploitation Strategy Seminar with Horizon Results Booster Jun 27, 2024 Maximising Project Impact: Effective Exploitation Strategies On 26 June 2024, iPROLEPSIS held an online Exploitation strategy seminar led by Horizon Results Booster expert Emmanuel Sofianopoulo. The seminar focused on introducing consortium partners to exploitation concepts and helping to develop an exploitation strategy for project results. Key points covered included: Introduction to exploitation and exploitation plans, Key Exploitable Results (KER), and the difference between exploitation and dissemination. We also participated in a workshop for a specific KER, involving: A session to introduce the KER. Further development and refinement of the Characterisation Table, risk map and outlining the Exploitation Roadmap. Excited to apply these strategies as we move forward with our project goals! 1/8 PREVIOUS NEXT

< BACK iPROLEPSIS Newsletter No. 6 Oct 9, 2024 Latest News from iPROLEPSIS Welcome to the 6th edition of the iPROLEPSIS newsletter. In this edition, we share the latest updates and progress from our project, including new developments, recent publications, and reflections on key events. iPROLEPSIS project newsletter_October 2024_ Issue No. 6 .pdf Download PDF • 4.41MB 1/1 PREVIOUS NEXT

< BACK iPROLEPSIS Newsletter No. 5 Jul 10, 2024 Discover Insights from Clinicians, Collaborative Efforts, and Key Events Welcome to the fifth edition of the iPROLEPSIS project newsletter. In this issue, we bring you insightful interviews with clinicians specialising in psoriatic arthritis, insights into recent clustering and networking activities, and reflections on key past events. iPROLEPSIS_Newsletter No. 5 .pdf Download PDF • 8.01MB 1/1 PREVIOUS NEXT

< BACK Trustworthy AI in Digital Health: The iPROLEPSIS Approach Mar 28, 2025 iPROLEPSIS at Health Data Summit 2025 At Health Data Summit 2025 , organised by The European Institute for Innovation Through Health Data on March 18–19 in Brussels , Vasileios Charisis, PhD , from the Signal Processing & Biomedical Technology Unit - AUTH , presented iPROLEPSIS during the session “Trustworthy AI in Digital Health: From Guidelines to Practice”. The presentation outlined the methodology used in iPROLEPSIS to develop a trustworthy AI (TAI) framework tailored to the project’s specific needs. A case study on the Lifestyle Recommendation Engine demonstrated how it aligns with TAI principles and recommendations . The session also featured other Horizon Europe projects , including AI-PROGNOSIS, TRUSTroke, and STRATIFYHF , which presented their approaches to developing trustworthy digital health solutions . By bringing together different initiatives, the session highlighted the importance of trustworthy AI in healthcare , ensuring transparency, reliability, and ethical considerations in digital health innovations . 1/3 PREVIOUS NEXT