Learning Hub

< BACK Insights from the Psoriasispatiënten Nederland Information Afternoon Nov 11, 2024 Reflection on the recent information afternoon for patients with psoriasis and psoriatic arthritis hosted by Psoriasispatiënten Nederland On 9 November 2024, in celebration of World Psoriasis Day , Psoriasispatiënten Nederland (Psoriasis Patients Netherlands) hosted an informative event in Nijkerk (the Netherlands). With over 90 attende es, the event was a great success, offering valuable insights and fostering connections among patients, clinicians, and researchers. The event aimed to offer the latest information on psoriasis and psoriatic arthritis while fostering discussions on treatment options and research advancements. A diverse range of expert presentations and interactive sessions enhanced attendees' understanding and contributed to improving patient care. During breaks, participants had the opportunity to visit several information stands and engage with researchers and specialists. iPROLEPSIS was represented by Jolanda Luime ( Erasmus MC ) , who shared insights into the ongoing research project focused on the prevention and early diagnosis of psoriatic arthritis. The event proved to be an insightful and inspiring day, bringing together a diverse group of patients, researchers, and healthcare professionals. The discussions, networking opportunities, and practical sessions contributed to a deeper understanding of psoriatic arthritis and psoriasis, making it a valuable experience for all involved. Read more: Terugblik op de afgelopen informatiemiddag - Psoriasispatiënten Nederland 1/6 PREVIOUS NEXT

< BACK iPROLEPSIS presented at the COMFORT-EU Plenary Meeting May 19, 2025 Strengthening Collaboration in AI for Healthcare Dr. Vasileios Charisis (Aristotle University of Thessaloniki) recently took part in the 2nd Plenary Meeting of the COMFORT-EU project (15–16 May 2025), where he presented the iPROLEPSIS project and introduced our work on a Trustworthy AI framework for healthcare. Meetings like this offer a valuable opportunity to connect with other research teams, share knowledge, and explore ways to collaborate. In the fast-evolving field of AI in healthcare , collaboration is essential — helping us learn from each other and develop better, safer solutions for real-world use. We are excited to continue working with COMFORT-EU and other Horizon Europe projects to drive innovation that benefits both science and society. 2.jpg 2.jpg 1/1 PREVIOUS NEXT

< BACK iPROLEPSIS 5th Plenary Meeting in Athens Dec 5, 2024 Advancing the Development of Digital Solutions for Psoriatic Arthritis Care The iPROLEPSIS consortium gathered in Athens, Greece, on 2-3 December 2024, for the 5th Plenary Meeting. Hosted by Netcompany-Intrasoft and Wellics, this two-day event brought together consortium partners, the External Advisory Board (EAB), and the Project Officer (PO) to discuss key updates and map out the next steps in developing a personalised digital care ecosystem for people with Psoriatic Arthritis (PsA). The meeting focused on project updates, key achievements, and future plans for the Psoriatic Arthritis digital care ecosystem. Day 1 covered progress in the project, co-creation activities, and updates from various work packages. The team also demonstrated the iPROLEPSIS tools, including the miPROLEPSIS apps, HCP’s dashboard, and the Lifestyle Recommendation System. On Day 2, workshops were held on study designs, ecosystem development, and predictive models. Discussions also focused on data governance and dissemination strategies. 1/8 PREVIOUS NEXT

< BACK Exploring the iPROLEPSIS Project: Insights from J. Luime Sep 17, 2024 Innovative Approaches to Monitoring and Managing Psoriatic Arthritis Jolanda Luime, senior researcher and project partner from Erasmus MC (the Netherlands), shares insights on the iPROLEPSIS project. The iPROLEPSIS project represents a significant advancement in the field of psoriatic arthritis research. By leveraging cutting-edge technology, including smartphones and data analysis, iPROLEPSIS aims to transform how we measure and understand psoriatic arthritis activity. Traditional methods of tracking psoriatic arthritis often fall short in capturing the full scope of the disease’s impact. iPROLEPSIS seeks to address this gap by exploring new and innovative approaches. The project uses advanced technology to monitor movement patterns and other key indicators of disease activity, offering a more comprehensive view of how the condition affects patients on a daily basis. One of the core objectives of iPROLEPSIS is to empower patients with better tools for managing their condition. By providing more detailed insights into disease activity, the project aims to help patients make informed decisions about their health and potentially prevent disease flares before they occur. This proactive approach has the potential to significantly improve the quality of life for those living with psoriatic arthritis. In addition to benefiting patients, iPROLEPSIS aims to to support clinicians by offering more accurate and actionable data. With better insights into disease activity and treatment effectiveness, healthcare providers can make more informed decisions regarding medication adjustments and overall treatment strategies. This not only enhances patient care but also helps streamline clinical practices, making the process more efficient and effective. Through the iPROLEPSIS project, the aim is to provide patients and clinicians with the tools they need to better understand and manage psoriatic arthritis, ultimately improving both patient outcomes and clinical practices. 1/1 PREVIOUS NEXT

< BACK Patient Voices in Research: Elaine’s Das Cheppo Journey with iPROLEPSIS Mar 4, 2025 A Patient’s Perspective: Elaine’s Journey with iPROLEPSIS Elaine Das Cheppo has been living with psoriatic arthritis for 25 years . Like many others, her diagnosis was delayed, making treatment more challenging in the early years. When her rheumatologist asked if she would like to take part in the iPROLEPSIS project , she did not hesitate. "I struggled in the beginning to understand why I was experiencing so much joint pain. By participating in this study, I hope to help future generations get a diagnosis faster than I did." The Role of Patient Partners in iPROLEPSIS Elaine is a patient partner in iPROLEPSIS, working alongside researchers to improve psoriatic arthritis care. She finds the co-creation sessions particularly insightful, offering her a behind-the-scenes look at how digital health solutions are developed. "It’s interesting to see how new technology is being used to improve diagnosis and treatment. These innovations could help people avoid unnecessary doctor visits and manage their condition more effectively." A Renewed Sense of Purpose For Elaine, being part of iPROLEPSIS is not just about contributing to research—it’s also about personal fulfillment . "For someone who has been retired for quite some time, it’s rewarding to have a new goal and interest in life. Being part of this project gives me a way to make a difference." Watch Elaine’s full story here: 1/1 PREVIOUS NEXT

< BACK Can ChatGPT provide appropriate meal plans for NCD patients? May 30, 2024 Assessing ChatGPT's Capability to Generate Personalised Meal Plans for Managing Non-Communicable Diseases Dietary habits significantly affect health conditions and are closely related to the onset and progression of non-communicable diseases (NCDs). Consequently, a well-balanced diet plays an important role in lessening the effects of various disorders, including NCDs. Several artificial intelligence recommendation systems have been developed to propose healthy and nutritious diets. Most of these systems use expert knowledge and guidelines to provide tailored diets and encourage healthier eating habits. However, new advances in large language models such as ChatGPT, with their ability to produce human-like responses, have led individuals to search for advice in several tasks, including diet recommendations. This study aimed to determine the ability of ChatGPT models to generate appropriate personalized meal plans for patients with obesity, cardiovascular diseases, and type 2 diabetes. Read the full publication: https://zenodo.org/records/13143043 1/1 PREVIOUS NEXT

< BACK iPROLEPSIS Games Pitch video from HiTech 2025 Jul 24, 2025 iPROLEPSIS Games presented during the HiSeedTech programme The iPROLEPSIS Games were presented at HiTech 2025 , a program by HiSeedTech. The pitch introduced the use of serious games to support treatment for Psoriatic Arthritis (PsA) , focusing on symptoms like mobility, pain, breathing, and emotional well-being. Watch the presentation here: HiTech 2025.png HiTech 2025.png 1/1 PREVIOUS NEXT

< BACK iPROLEPSIS Sensorimotor Games Presented at DSAI 2024 Nov 20, 2024 Innovative digital games designed to support people with Psoriatic Arthritis presented at an international ICT conference. The iPROLEPSIS project coordinator, Prof. Leontios Hadjileontiadis, presented the iPROLEPSIS Sensorimotor Games at the 11th International Conference on Software Development and Technologies for Enhancing Accessibility and Fighting Info-exclusion (DSAI 2024) . The conference was held from 13–15 November at Khalifa University in Abu Dhabi, United Arab Emirates (UAE). The Sensorimotor Games are interactive digital applications designed for more than just entertainment. They combine enjoyment with skills training, social impact, and health improvement. As part of a personalised game suite, these games aim to support people living with Psoriatic Arthritis (PsA), offering a unique approach to enhancing their quality of life. DSAI is a leading international forum focused on accessible and usable Information and Communication Technologies (ICT). The conference provided an excellent platform to share progress on the iPROLEPSIS project and highlight its innovative approach to digital healthcare solutions. 1/2 PREVIOUS NEXT

< BACK iPROLEPSIS at IEEE HealthCom 2025: AI-Enabled Digital Health for Psoriatic Arthritis Nov 3, 2025 Project researchers presented new studies, co-chaired a workshop, and joined a panel on digital innovation in healthcare in Abu Dhabi The iPROLEPSIS team participated in the IEEE HealthCom 2025 Conference , held 21–23 October 2025 and hosted by Khalifa University in Abu Dhabi, United Arab Emirates . The event gathered international experts in digital health , artificial intelligence , and biomedical technologies to discuss how AI can improve the understanding and management of non-communicable diseases . Modeling joint swelling through smartphone photographs Giorgos Apostolidis from the Signal Processing & Biomedical Technology Unit – AUTH presented the paper “Modeling Interphalangeal Joints for Swelling Assessment in Psoriatic Arthritis via Smartphone Photographs”. By analyzing smartphone photos of hands, the study showcased that a digital estimation of joint thickness, namely effective width , with the aid of a logistic regression model , can serve as an effective tool for detecting interphalangeal joint swelling in people with PsA .This approach was validated on a real-world dataset collected within the PDPID study . Giorgos Apostolidis (Signal Processing & Biomedical Technology Unit – AUTH) Designing exergames for Psoriatic Arthritis care Prof. Leontios Hadjileontiadis (AUTH) presented the paper “Designing Exergames for Psoriatic Arthritis: The Spy and Zen Forest Paradigms”. The Spy and Zen Forest exergames were co-designed to complement PsA care by making therapeutic exercises more engaging and accessible at home. Using real-time body tracking on mobile devices , these games promote dynamic movement to enhance mobility and strength, and calm stretching for flexibility and relaxation. Prof. Leontios Hadjileontiadis (Signal Processing & Biomedical Technology Unit-AUTH) Panel discussion: Digital Bridges for Better Health Project Coordinator Prof. Leontios Hadjileontiadis , Scientific & Technical Manager Vasileios Charisis , and Stelios Hadjidimitriou from the Signal Processing & Biomedical Technology Unit – AUTH , together with Dr. Kosmas Dimitropoulos from the Centre for Research & Technology Hellas (CERTH) and Prof. Mohamed Seghier from Khalifa University , participated in the panel discussion “Digital Bridges for Better Health: AI Innovation from Europe to the Middle East and North Africa (MENA),” moderated by Giorgos Apostolidis. The panel provided insights into: The technical challenges in integrating AI with existing healthcare IT systems, How key stakeholders can collaborate to ensure AI digital health tools are user-friendly and clinically relevant, The role of patient engagement and digital literacy in the effectiveness of AI tools in chronic disease management How socio-cultural differences between Europe and MENA can influence the design and adoption of AI digital health solutions What are the key regulatory challenges in Europe and MENA regarding the use of AI in healthcare and what joint efforts can be undertaken to harmonize standards in these regions During the session, the iPROLEPSIS project and its AI-enabled digital health tools for assisting Psoriatic Arthritis management and care were highlighted as a case study of AI solutions with potential to improve outcomes for people with non-communicable diseases . Panel discussion "Digital Bridges for better health: AI Innovation from Europe to the Middle East and North Africa (MENA)" Workshop chairing Scientific & Technical Manager Vasileios Charisis from the Signal Processing & Biomedical Technology Unit-AUTH co-chaired the workshop "AI-enabled Digital Health Tools for Non-Communicable Diseases: From Concepts to Impact" . The workshop was co-organised with the AI-PROGNOSIS Horizon Europe project and included research works in the fields of psoriatic arthritis, Parkinson's disease, multiple sclerosis and post-stroke rehabilitation. Two of the presented papers stem from research carried out within iPROLEPSIS: Apostolidis et al., Modeling Interphalangeal Joints for Swelling Assessment in Psoriatic Arthritis via Smartphone Photographs Ramalho et al., Designing exergames for psoriatic arthritis: The Spy and Zen Forest paradigms Workshop “AI-enabled Digital Health Tools for Non-Communicable Diseases: From Concepts to Impact” The iPROLEPSIS and AI-PROGNOSIS teams from AUTH participated jointly at IEEE HealthCom 2025 , highlighting their shared commitment to advancing AI-enabled digital health solutions that enhance the understanding, early detection, and management of chronic diseases . iPROLEPSIS and AI-PROGNOSIS team members PXL_20251021_131742947.MP.jpg 2.jpg IMG_2954.jpg PXL_20251021_131742947.MP.jpg 1/11 PREVIOUS NEXT

< BACK iPROLEPSIS Research on Digital Rheumatology Published in The Lancet eClinicalMedicine May 19, 2025 New Publication Highlights Explainable AI Tools, Digital Biomarkers, and Multimodal Disease Monitoring for PsA A recent paper published in The Lancet eClinicalMedicine presents the iPROLEPSIS initiative as a comprehensive European research effort aimed at transforming the diagnosis and management of psoriatic arthritis (PsA) through digital innovation and patient-centred care . The paper, titled "European advances in digital rheumatology: explainable insights and personalized digital health tools for psoriatic arthritis", outlines how iPROLEPSIS addresses critical gaps in current PsA care by combining real-world data , wearable sensors , and explainable artificial intelligence (xAI) models. Abstract The shift from traditional to technology-based diagnosis and management of psoriatic arthritis (PsA) represents a significant evolution in patient care. Traditionally, PsA was diagnosed and managed through clinical evaluations, physical examinations, and basic imaging techniques. With the evolution of digital technologies, PsA care is transforming, giving rise to the field of digital rheumatology. In this vein, Europe has invested in research initiatives, like iPROLEPSIS, that could accelerate this transformation and redefine PsA care within a digital world. In this Viewpoint we present the current clinical PsA landscape, highlight the PsA patients’ interaction with the digital world, and showcase the novel iPROLEPSIS digital offerings. The latter scaffold digital rheumatology by identifying PsA key drivers. Moreover, they support personalized PsA risk prediction and improve early PsA detection. Furthermore, they enable precise PsA treatment strategies and digital therapeutics within a novel digital health ecosystem. Read the full paper here: https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(25)00175-0/fulltext PIIS2589537025001750 .pdf Download PDF • 1.20MB Lancet publication.png Lancet publication.png 1/1 PREVIOUS NEXT

< BACK iPROLEPSIS presented at the MULTIPULM project kick-off meeting Oct 8, 2025 iPROLEPSIS tools to be adapted for clinical studies in Brazil, Serbia, and Türkiye The iPROLEPSIS project was presented during the kick-off meeting of the MULTIPULM project, held on 29–30 September in Athens. iPROLEPSIS partners Aristotle University of Thessaloniki (AUTH) , Faculdade de Motricidade Humana (FMH) , and Wellics participated in the meeting, which brought together researchers, clinicians, user research experts, and technology providers. Several tools developed within iPROLEPSIS – including the breathing games created by FMH and the biAURA app developed by AUTH – will be further used in MULTIPULM. These tools will be adapted to the local needs of the project’s pilot sites in Brazil, Serbia, and Türkiye, and evaluated in relevant clinical studies. This collaboration demonstrates the adaptability and broader potential of iPROLEPSIS digital tools beyond psoriatic arthritis, supporting research in other chronic conditions. SPBTU_KoM_MULTIPULM_Athens.jpg ae74e3_e25adf83abf6411cace29ed99801554f~mv2.jpg SPBTU_KoM_MULTIPULM_Athens.jpg 1/2 PREVIOUS NEXT

< BACK iPROLEPSIS at the 2nd Healthy Longevity Symposium Nov 21, 2024 Showcasing the Serious Game Suite for PsA at the Healthy Longevity Symposium The iPROLEPSIS project coordinator, Prof. Leontios Hadjileontiadis , presented the Serious Game Suite for Psoriatic arthritis patients at the 2nd Healthy Longevity Symposium , held by Khalifa University in Abu Dhabi on 21-22 November 2024. The symposium gathered leading experts to explore key topics related to longevity and aging, which is recognised as the root cause of many chronic diseases. The event focused on the latest advancements in aging mechanisms, genomic precision medicine, rejuvenation, and social health policies. Discussions highlighted the potential of AI, advanced technologies, and precision medicine to address the challenges of aging, slow age-related diseases, and improve overall well-being. By integrating cutting-edge research and technology, iPROLEPSIS is advancing innovative solutions aimed at improving the lives of people living with PsA. 1/2 PREVIOUS NEXT