Apr 23, 2026
A poster presented in Rotterdam highlighted cross-country harmonization of psoriatic arthritis cohorts into the OMOP Common Data Model
At the European OHDSI Symposium 2026 in Rotterdam, project partner AINIGMA presented a poster entitled Cross-Country Harmonization of Psoriatic Arthritis Cohorts: A Real-World Data Study in the context of the iPROLEPSIS project.
Psoriatic arthritis affects 1–2% of the population and shows substantial heterogeneity in symptoms, progression, and treatment response. Real-world evidence is essential to understand long-term outcomes, sex differences, and disease trajectories that are difficult to capture in clinical trials.
To identify key inflammation drivers, the team harmonised two national psoriatic arthritis cohorts – the Portuguese Reuma.pt registry and the Dutch DEPAR cohort – into the OMOP Common Data Model (OMOP CDM). This enabled standardised cross-country and sex-stratified analyses.
The poster also presented data quality results for this harmonisation work, showing a 95% overall pass rate, including 99% for plausibility, 88% for conformance, and 90% for completeness.
As highlighted in the conclusion of the poster, this work shows the value of harmonising data from different national psoriatic arthritis registries into the OMOP CDM to make standardised real-world analyses across European healthcare systems possible. It also opens up new possibilities for advanced analytics, such as federated studies and AI-driven prediction models, beyond this proof-of-concept analysis, advancing iPROLEPSIS’s goal of personalised, data-driven care.
