Download needed deliverables for iProlepsis project for psoriatic arthritis. Project deliverables D1.2 Data managmeent plan (initial version) WP1 - Management and coordination Read More D2.3 The iPROLEPSIS trustworthy AI framework WP2 - Knowledge mining, foundation and participatory design Read More D3.1 First report on PsA inflammation drivers research WP3 - Research on PsA inflammation drivers and monitoring Read More D4.4 The iPROLEPSIS serious gaming suite (alpha version) WP4 - Development of the iPROLEPSIS digital health ecosystem for personalised preventive care Read More D6.2 Dissemination, exploitation and communication plan WP6 - Dissemination, communication and exploitation Read More D6.8 Update on the Dissemination, Exploitation and Communication Plan WP6 - Dissemination, communication and exploitation Read More D2.1 Initial report on user research and co-creation process WP2 - Knowledge mining, foundation and participatory design Read More D2.4 Updated report on the state-of-the-art and datasets WP2 - Knowledge mining, foundation and participatory design Read More D3.2 First report on digital phenotyping for PsA WP3 - Research on PsA inflammation drivers and monitoring Read More D5.1 Study initiation package (iPROLEPSIS-PDPID study) WP5 - Clinical studies Read More D6.3 First report on project visibility and educational material WP6 - Dissemination, communication and exploitation Read More D2.2 Initial report on the state-of-the-art and datasets WP2 - Knowledge mining, foundation and participatory design Read More D2.5 Updated report on user research and co-creation process WP2 - Knowledge mining, foundation and participatory design Read More D4.2 The iPROLEPSIS patient and HCP apps (study version) WP4 - Development of the iPROLEPSIS digital health ecosystem for personalised preventive care Read More D6.1 Project branding and communication channels WP6 - Dissemination, communication and exploitation Read More D6.5 Midterm report on project visibility and educational material WP6 - Dissemination, communication and exploitation Read More

Learning how to live with psoriatic arthritis might feel like a challenge. But understanding your diagnosis can help you take control of your health. Learning Hub Explore resources to help you understand and manage psoriatic arthritis. Learning hub Key Facts Handbook News Feed Quizzes Search Psoriatic Arthritis Key Facts Key Facts Quizzes about Psoriatic Arthritis Take a Quiz Search about Psoriatic Arthritis Search Psoriatic Arthritis Handbook Handbook News Feed about Psoriatic Arthritis News Feed

< BACK "The Kite" Breathing Serious Game: Agile Co-Design for Psoriatic Arthritis Jul 31, 2024 Enhancing PsA Management through Innovative Breathing Exercises and Game-Based Therapy Latest research initiative under the iPROLEPSIS project: “The Kite” Breathing Serious Game: Agile Co-Design for Psoriatic Arthritis presented at IEEE MELECON 2024. This study is part of a broader effort to develop and validate innovative digital biomarkers for managing Psoriatic Arthritis (PsA) through the Artificial Intelligence-Personalised Game Suite (AI-PGS). Abstract: Serious Games (SGs) have the potential to provide clinical care and enhance patients’ quality of life, while incorporating an element of entertainment. As part of the iPROLEPSIS Horizon Europe project, we introduce two Sensorimotor Art games designed as SGs to assist Psoriatic Arthritis (PsA) patients in managing their symptoms. These SGs provide a platform for self-expression and pain relief through engaging in rhythmic puzzle activities. The co-design process for the proposed Sensorimotor Art games followed an agile methodology, involving 14 experts (including clinicians, researchers, and game developers), to gather feedback on game requirements, storyboards, and mechanics. From the thematic analysis of the transcribed discussion, four main themes emerged, namely: Clinical value (Theme 1), Motor skills and adaptation (Theme 2), Creative engagement (Theme 3), and Feedback and future directions (Theme 4). Clinical value underlines the therapeutic benefits of Sensorimotor Art games for pain distraction and emotional well-being. Motor skills and adaptation focus on hand/finger use and adapting games for older patients. Creative engagement emphasizes fostering creativity, a positive environment, and goal achievement. Finally, feedback and future directions highlight the importance of continuous feedback and occupational therapists’ involvement in coming sessions. The development of Sensorimotor Art games lays the groundwork for digital interventions to alleviate psychological distress and improve fine motor symptoms in PsA patients. At the same time, these SGs can also provide insights to healthcare providers and policymakers for developing future digital solutions tailored to PsA patients. Read the full publication: https://zenodo.org/records/13141465 IEEE_MELECON_2024 .pdf Download PDF • 1.33MB 1/1 PREVIOUS NEXT

< BACK iPROLEPSIS Newsletter No. 5 Jul 10, 2024 Discover Insights from Clinicians, Collaborative Efforts, and Key Events Welcome to the fifth edition of the iPROLEPSIS project newsletter. In this issue, we bring you insightful interviews with clinicians specialising in psoriatic arthritis, insights into recent clustering and networking activities, and reflections on key past events. iPROLEPSIS_Newsletter No. 5 .pdf Download PDF • 8.01MB 1/1 PREVIOUS NEXT

< BACK iPROLEPSIS Newsletter No. 8 Apr 28, 2025 Latest News from iPROLEPSIS Welcome to the eighth edition of the iPROLEPSIS newsletter, where we share the latest updates and progress from the project. iPROLEPSIS project newsletter Issue No. 8_Apr 2025 .pdf Download PDF • 3.38MB 1/1 PREVIOUS NEXT

Learning Hub Explore resources to help you understand and manage psoriatic arthritis. Learning hub Key Facts Handbook News Feed Quizzes Search How is psoriatic arthritis diagnosed? See related Handbook section PREVIOUS NEXT

< BACK iPROLEPSIS Innovative Federated Learning Approach at IEEE IST 2023 Oct 23, 2023 Enhancing Federated Learning Through Advanced Weight Distribution Analysis IEEE International Conference on Imaging Systems and Techniques (IST) conference served as a platform for presenting iPROLEPSIS research in federated learning, specifically focusing on novel methods for weight aggregation. Title: Federated Learning Aggregation based on Weight Distribution Analysis Abstract: Federated learning has recently been proposed as a solution to the problem of using private or sensitive data for training a central deep model, without exchanging the local data. In federated learning, local models are trained on the client side using the available data, while a server is responsible for aggregating the weights of these models into a global model. However, the traditional weight averaging approach does not take into consideration the importance of the different weights for the performance of a model. To this end, this work proposes a novel federated learning weight aggregation method that estimates the statistical distance of each client's parameters from the Gaussianity, and weighs the contribution of each client to the global model accordingly so that the most significant information is retained and enhanced. To create an accurate global model, a complex weighted averaging of the parameters of clients' models at the layer level is performed, considering as low quality the parameters following the Gaussian distribution. The proposed method can be employed to both convolutional and linear layers and it is based on the notion that parameters following a Gaussian distribution do not significantly affect the output of a model. Experiments with different network architectures and a comparison with a plethora of state-of-the-art approaches on three well-known image classification datasets demonstrate the superiority of the proposed method for federated learning weight aggregation. Read the full publication here: (PDF) Federated Learning Aggregation based on Weight Distribution Analysis ( researchgate.net ) https://ieeexplore.ieee.org/document/10355708 1/1 PREVIOUS NEXT

< BACK Europe Day 2024 May 9, 2024 Celebrating Europe Day with iPROLEPSIS sister projects Happy Europe Day 2024! Today we celebrate unity in diversity, innovation and collaboration across the continent. As projects funded under the same Horizon Europe call topic: "Personalised blueprint of chronic inflammation in health-to-disease transition", we're proud to contribute to the common goals of understanding the risk factors that trigger the transition from health to disease, providing personalised prevention measures and reducing the burden of chronic diseases. Within iPROLEPSIS , we aim to develop a suite of digital health tools designed to detect early transitions to psoriatic arthritis, predict flares for timely intervention, and provide personalised recommendations and interventions for managing the disease. With our unique consortium of 15 partners from 9 countries, we are strengthening international and cross-border collaboration to advance research, technology and health progress in Europe and beyond. Join us in commemorating this special day by exploring the impactful work of our sister projects: GlycanTrigger , ENDOTARGET , IMMEDIATE , miGut-Health , AIDA EU project , PREVALUNG EU , PRAESIIDIUM , CARE-IN-HEALTH , Intercept-T2D , INITIALISE , Halt-RONIN , Together, we're shaping a brighter, more inclusive, and sustainable Europe through groundbreaking research and cross-border connections. Europe Day sister projects .png Europe Day sister projects .png 1/1 PREVIOUS NEXT

< BACK iPROLEPSIS Showcased at MEDICA 2025 Nov 25, 2025 Project presented by PLUX at an international medical technology trade fair MEDICA 2025 was held in Düsseldorf, Germany, from 17–20 November 2025 and is one of the largest international trade fairs for medical technology and healthcare. iPROLEPSIS was showcased by project partner PLUX at MEDICA 2025, within a shared exhibition space alongside other Portuguese entities. The event offered an opportunity to present the project to industry and healthcare stakeholders and to engage with a broad international audience. MEDICA 2025 2.HEIC MEDICA 2025 1.HEIC MEDICA 2025 2.HEIC 1/2 PREVIOUS NEXT

< BACK iPROLEPSIS 3rd Plenary Meeting Nov 30, 2023 iPROLEPSIS 3rd Plenary Meeting in Rotterdam: 12-13 December 2023 On 12-13 December 2023, iPROLEPSIS partners will meet in Rotterdam for the third plenary meeting. The agenda includes workshops on the PDPID study, digital biomarkers, technical ecosystem development, serious games co-creation, an External Advisory Board session, and more. Stay tuned for updates on our progress! iPROLEPSIS 3rd Plenary meeting (1).png iPROLEPSIS 3rd Plenary meeting (1).png 1/1 PREVIOUS NEXT

< BACK Insights from the Psoriasispatiënten Nederland Information Afternoon Nov 11, 2024 Reflection on the recent information afternoon for patients with psoriasis and psoriatic arthritis hosted by Psoriasispatiënten Nederland On 9 November 2024, in celebration of World Psoriasis Day , Psoriasispatiënten Nederland (Psoriasis Patients Netherlands) hosted an informative event in Nijkerk (the Netherlands). With over 90 attende es, the event was a great success, offering valuable insights and fostering connections among patients, clinicians, and researchers. The event aimed to offer the latest information on psoriasis and psoriatic arthritis while fostering discussions on treatment options and research advancements. A diverse range of expert presentations and interactive sessions enhanced attendees' understanding and contributed to improving patient care. During breaks, participants had the opportunity to visit several information stands and engage with researchers and specialists. iPROLEPSIS was represented by Jolanda Luime ( Erasmus MC ) , who shared insights into the ongoing research project focused on the prevention and early diagnosis of psoriatic arthritis. The event proved to be an insightful and inspiring day, bringing together a diverse group of patients, researchers, and healthcare professionals. The discussions, networking opportunities, and practical sessions contributed to a deeper understanding of psoriatic arthritis and psoriasis, making it a valuable experience for all involved. Read more: Terugblik op de afgelopen informatiemiddag - Psoriasispatiënten Nederland 1/6 PREVIOUS NEXT

< BACK Advancing Digital Health Solutions: Updates on User Research and Co-Creation Nov 20, 2023 Navigating the Development of PDPID-App, Insights from Co-Creation Sessions Updates on user research and co-creation The current status of user research and co-creation involves a dedicated focus on advancing the development of the PDPID-app , scheduled for delivery before January 2023. In early October 2023, Erasmus MC ( EMC) conducted a co-creation session with patient partners to assess the general looks and feel of the User Interface (UI) and identify points to improve the app's usability. In apps used for medical data collection, it is of utmost importance that users know what is expected of them. Furthermore, users should be engaged with the app to a level that minimises missing data. Following this, bi-weekly meetings with patient partners were established to maintain alignment with their ideas. Furthermore, project partner FACULDADE DE MOTRICIDADE HUMANA (FMH-ULISBOA) is developing storyboards for the personalised gaming suite . Three co-creation sessions have been executed: one with healthcare professionals and two with patient partners. Additionally, project partners The Centre for Research and Technology Hellas (CERTH) and FACULDADE DE MOTRICIDADE HUMANA (FMH-ULISBOA) have been working with the clinical partners to identify movements for the video analysis tasks that will be included in the iPROLEPSIS-PDPID study. Multiple hand gestures and full-body movements have been identified for further assessment. Key take-away messages The development of the Digital health tools is still at an early stage. However, several take-away messages from the discussions about the PDPID app are : The general looks and UI of the miPROLEPSIS app have been approved by the patient partners. Even though the PDPID-app is a data-collection app for research purposes, patients find it of utmost importance that they can review their own data entries. Participants indicated that the app needs to improve its’ visual cues of when they need to perform certain activities. Take-away messages from the discussions about personalised gaming suite development: Smart games meant for disease management should be highly tailored to the capabilities of the patients. Gaming is for patients a way of relaxation, any game designed should not incorporate any stressful factors. Patient partners expressed interest in the proposed gaming categories. Future steps Future steps involve initiating a round of user testing for the PDPID version of the miPROLEPSIS app to validate designs with patients not involved in the development process. Subsequently, attention will shift to developing recommendation systems for physical activity and diet, incorporating insights from experts in the field (occupational therapists, physical therapists & nutritionists) and patients themselves. For the personalised gaming suite, the completion of the storyboard is planned for the end of December 2023, when the development of the first prototypes will follow. mIPROLEPSIS app.png mIPROLEPSIS app.png 1/1 PREVIOUS NEXT