< BACK Highlights from IEEE EMBS 2024 Sep 5, 2024 Showcasing AI-Based Solutions for Psoriatic Arthritis Care Our project partner, PLUX Biosignals, participated in the 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS) , held in Orlando, Florida, USA, from July 15-19, 2024. During this prestigious event, PLUX presented the innovative work of the iPROLEPSIS project, which focuses on developing a novel, personalised digital care ecosystem for individuals with psoriatic arthritis. The world's largest international biomedical engineering conference, IEEE EMBS 2024 featured an extensive range of scientific tracks covering cutting-edge research and innovations in biomedical engineering and healthcare technology. Topics included women and children's health, translational clinical research, technology transfer, entrepreneurship, and biomedical engineering education. This event provided a valuable platform for showcasing the potential of AI-based solutions in improving care for psoriatic arthritis patients and highlighted the role of digital tools in revolutionizing personalised healthcare. 1/2 PREVIOUS NEXT

< BACK Can ChatGPT provide appropriate meal plans for NCD patients? May 30, 2024 Assessing ChatGPT's Capability to Generate Personalised Meal Plans for Managing Non-Communicable Diseases Dietary habits significantly affect health conditions and are closely related to the onset and progression of non-communicable diseases (NCDs). Consequently, a well-balanced diet plays an important role in lessening the effects of various disorders, including NCDs. Several artificial intelligence recommendation systems have been developed to propose healthy and nutritious diets. Most of these systems use expert knowledge and guidelines to provide tailored diets and encourage healthier eating habits. However, new advances in large language models such as ChatGPT, with their ability to produce human-like responses, have led individuals to search for advice in several tasks, including diet recommendations. This study aimed to determine the ability of ChatGPT models to generate appropriate personalized meal plans for patients with obesity, cardiovascular diseases, and type 2 diabetes. Read the full publication: https://zenodo.org/records/13143043 1/1 PREVIOUS NEXT

Learning Hub Explore resources to help you understand and manage psoriatic arthritis. Learning hub Key Facts Handbook News Feed Quizzes Search How will psoriatic arthritis affect me? Emotional wellbeing See related Handbook section PREVIOUS NEXT

< BACK World Psoriasis Day: iPROLEPSIS featured by HaDEA Oct 29, 2025 On World Psoriasis Day, the European Health and Digital Executive Agency (HaDEA) highlights how the iPROLEPSIS project is advancing early detection and personalised care for psoriatic arthritis Psoriatic arthritis (PsA) is a chronic inflammatory condition that can cause irreversible joint damage if left undiagnosed or untreated. To address this challenge, iPROLEPSIS is developing AI-driven predictive models and digital tools that help identify individuals at risk, enable earlier diagnosis, and support more personalised treatment pathways. In a recent interview with Prof. Leontios Hadjileontiadis , project coordinator, HaDEA explores how iPROLEPSIS brings together clinicians, researchers, and data scientists to transform psoriatic arthritis management across Europe. The discussion covers the project’s use of AI and biological data to build comprehensive patient profiles, its collaborative approach between dermatology and rheumatology, and the importance of EU funding and ethical, cross-border cooperation in enabling innovation. Read the full article on HaDEA’s website: https://hadea.ec.europa.eu/news/world-psoriasis-day-exploration-how-horizon-europe-project-improving-early-detection-psoriatic-2025-10-29_en World Psoriasis Day 2025.png World Psoriasis Day 2025.png 1/1 PREVIOUS NEXT

Coordination team Vasilis Charisis Signal Processing & Biomedical Technology Unit (SPBTU) – Aristotle University of Thessaloniki Position Principal researcher focusing on the development of digital biomarkers and their translation into healthcare tools and interventions. What is your role in iPROLEPSIS? Scientific and Technical Coordinator. What are your main activities in the project? I manage the project's day-to-day operations and scientific coherence, driving the timely delivery of outcomes. Our team (SPBTU) is pioneering the use of AI and digital biomarkers from everyday smart devices to create predictive models for PsA symptoms. We are also developing a dedicated mobile app that supports patients by improving sleep patterns using binaural beat technology. What is your motivation? My motivation is rooted in a long-standing commitment to improving chronic disease management through accessible, non-invasive technology. In iPROLEPSIS, I am driven to apply advanced AI and biomedical engineering principles to address the significant challenges faced by PsA patients. We aim to create tangible, personalized digital tools that not only predict disease flares early but actively enhance patients' quality of life, ensuring our cutting-edge research delivers real clinical benefits. Coordination Clinical Experts Data Science Software Development Ethics, Legal and Exploitation Dissemination and Communication

Learning Hub Explore resources to help you understand and manage psoriatic arthritis. Learning hub Key Facts Handbook News Feed Quizzes Search Psoriatic Arthritis Handbook Living with Psoriatic Arthritis Handbook How will psoriatic arthritis affect me? WORK Work can provide a sense of purpose, identity, achievement, and a supportive social network, contributing positively to your emotional and physical wellbeing. While your condition may pose some challenges, people living with psoriatic arthritis can continue to work as long as their profession does not exacerbate their symptoms and worsen their health. People with certain health conditions have defined rights set out in law, designed to protect them against direct and indirect discrimination in the workplace. Your employer is legally obligated to make “reasonable accommodations” to your working environment and practices to ensure your condition does not prevent you from doing your job to the best of your ability and in a comfortable and safe environment. h3.1 In the European Union, the definition of reasonable accommodation at work was introduced by Article 5 of the Employment Equality Directive (Directive 2000/28/EC): “shall take appropriate measures, where needed in a particular case, to enable a person with disability to have access to, participate in, or advance in employment, or to undergo training, unless such measures would impose a disproportionate burden on the employer.” This directive has been transposed into national law in all EU member states. Research has shown that people who need workplace accommodations and effectively use them are more likely to keep a job and stay productive than those who do not use workplace accommodations (39). However, asking for workplace accommodations can be difficult. You may be concerned about being treated differently and negative reactions from your supervisor(s) or colleague(s). For this reason, you may prefer to negotiate informal workplace accommodations rather than seeking formal accommodations. Some of these accommodations may include those supported by the American College of Sports Medicine guidelines for physical activity and public health (40) and the ISO 11226 standard , https://www. iso.org/standard/25573.html , which defines joint limits to safeguard musculoskeletal health. By aligning workplace practices with these scientifically supported guidelines, employers and healthcare professionals can better accommodate the needs of their employees, fostering an inclusive and supportive work environment. Some examples follow: Recommendation #1: Avoid working for prolonged periods in the same position, whether sitting or standing. During the work shift: a continuous period of time in the standing position should not exceed 1 hour; the total time spent in a standing position should not exceed 4 hours; continuous sitting should be limited to 2 hours; when periods are dedicated to holding meetings, the duration of which should be reasonable, consideration should be given to the possibility of having them while standing or walking (41). Recommendation #2: Take frequent breaks throughout the shift. Please note that he definition of “breaks” must consider the following characteristics: Frequency: number of breaks/interruptions during the working day; Duration: micro-breaks (less than 2 minutes); short breaks (typically those that occur in the morning or afternoon, lasting between 7 and 10 minutes); or long breaks (meal breaks); and Type: passive or resting and active (including stretching or walking) (42). Thus, in an 8-hour working day, a worker should take at least a 7–10-minute break after consecutive 90-minute work periods. Recovery periods can include moments of rest or the performance of any other task to recover the muscle groups that have been worked. Within a period of at least 90 minutes, a worker should enjoy at least 30 seconds after 20 minutes of work. Both recommendations aim to address the prolonged exposure to low-intensity static load by limiting the duration of this exposure. These interventions help to alleviate fatigue and pain symptoms in the short-term, and to prevent work-related musculoskeletal injuries in the long-term. Active breaks add value; however, they do not replace the need to introduce diversity in the intensity of the mechanical load, such as rotational planes suited to the job’s demands (43). Please note that these recommendations refer to low-intensity, physically demanding tasks. Other recommendations apply to high-intensity tasks, such as those involving manual force. Recommendation #3: Physical changes to workstations work surfaces (desks) that allow alternation between standing and sitting, alone or combined with a training and information program for workers, reduce sitting time by approximately 60 minutes per working day (in the medium term, i.e., up to 3-12 months). This change in physical working conditions can bring about a behavioural change, with repercussions in an average reduction of 82 minutes in total sitting time per day (at and away from work) and in the average duration of consecutive periods of sitting (57 minutes) (42, 44). Even though workplace adaptations are consigned in the law, many people living with rheumatic and musculoskeletal diseases report a lack of understanding from their employer(s), colleague(s), and workplace doctor(s). You have options and rights; it is important to understand them and fully explore all available alternatives. If you are unsure about your rights in the workplace, please get in touch with your HR or occupational health department. More information can be found below: The Advisory, Conciliation and Arbitration Service. (ACAS) https://www.acas.org.uk/reasonable-adjustments If you require workplace adaptations, please talk to your assistant doctor about the difficulties you have been feeling and request reports to present to your employer and/or workplace doctor. See related Key Facts section SLEEP Pain, anxiety, and side effects of the medication can make it more difficult for a person with psoriatic arthritis to fall asleep and stay asleep throughout the night. In fact, about 40% of people living with psoriatic arthritis report sleep difficulties (45). Good sleep hygiene habits may help to improve sleep: develop a regular sleep routine, that is, go to bed and get up at a similar time each day; avoid caffeine, alcohol, and large meals before you go to bed; if you smoke, try to stop smoking, or at least do not smoke close to bedtime; a warm bath before bedtime may help ease pain and stiffness; listen to soothing music or sounds before going to bed; avoid watching TV and using computers, tablets, or smartphones in your bedroom; make sure your bedroom is dark, quiet, relaxing, and at a comfortable temperature. h3.2 The impact of exercising before bedtime can vary among individuals. It is essential to listen to your body, establish a consistent routine, and pay attention to how evening workouts affect your sleep patterns. If you have specific concerns about your sleep or exercise routine, it is also advisable to consult with a healthcare professional or a fitness expert. Pros: Improved sleep quality: For some people, engaging in moderate-intensity exercises a few hours before bedtime may promote better sleep quality. It can help reduce stress and anxiety, leading to a more relaxed state conducive to sleep. Body temperature regulation: Exercise increases body temperature, and the subsequent drop in temperature after exercise can signal the body that it is time to sleep. This mimics the natural temperature drop that occurs during the evening. Establishing a routine: Regular exercise, regardless of the time of day, can contribute to better sleep quality. Establishing a consistent exercise routine is often more important than the specific time of day. Cons: Stimulating effect: For some people, intense exercise close to bedtime may have a stimulating effect, making it more challenging to wind down and fall asleep. Body temperature: While the drop in body temperature after exercise can promote sleep, exercising too close to bedtime may disrupt the body’s natural cooling process, potentially interfering with sleep. Individual variability: People respond differently to exercise timing. Some may find that late-night workouts do not impact their sleep, while others may experience difficulties. Recommendations: Timing matters: Try to finish exercising at least 2-3 hours before bedtime to allow your body temperature to return to normal and your adrenaline levels to decrease. Listen to your body: Pay attention to how your body responds to evening workouts. It might be a good fit for you if it helps you relax and improves your sleep. Experiment: Everyone is different. Experiment with varying timings of exercise to see what works best for you. If evening workouts negatively impact your sleep, consider shifting them earlier. Moderation is key: Intense or vigorous exercise close to bedtime might be more likely to interfere with sleep. Opt for moderate-intensity activities in the evening (47). Nearly 50% of patients living with psoriatic arthritis report high levels of fatigue (five or higher on a 10-point scale) and consider fatigue a high-ranking problem, after joint pain and before skin issues (48). See related Key Facts section FATIGUE Problem solving, planning, prioritising, and pacing may help you cope better with your fatigue: PROBLEM SOLVING Identify factors / tasks / chores / activities that are contributing to your fatigue; Think about solutions that could help minimise the impact of these factors/tasks/chores/ activities. PLANNING Plan the tasks/chores/activities you want to complete in a day or week; Make sure to include activities that you enjoy and can improve your mood/wellbeing; Do not beat yourself up if you cannot stick to the plan. PRIORITISING Organise your tasks/chores/activities by order of importance. PACING Do not use your energy all in one go; Break the planned tasks/chores/activities into smaller portions that can be spread out over the course of a day, a week or even longer. See related Key Facts section EMOTIONAL WELLBEING Living with psoriatic arthritis can take a toll on your mental health (49, 50). You need to treat mental health symptoms as seriously as physical symptoms. Poor mental health can cause your psoriatic arthritis to flare, increase pain and fatigue, negatively affect your work and personal relationships, and limit your ability to manage your overall health. If you feel sad, hopeless, and lose interest in things you used to enjoy, talk to your doctor, and let your loved ones know what you are going through. Your doctor may redirect you to useful mental health services such as cognitive behavioural therapy (CBT) and/or they may prescribe you an antidepressant. h3.3 h3.4 Remember that you are not alone. If you need extra support, we are here to help you: NHS Mental Health Services https://www.nhs.uk/nhs-services/mental-health-services/ VERSUS ARTHRITIS / Psoriatic arthritis https://versusarthritis.org/ +44 800 520 0520 Be kind to your joints and your mind. See related Key Facts section See related Key Facts Previous page Next page

Download needed deliverables for iProlepsis project for psoriatic arthritis. Project deliverables D1.2 Data managmeent plan (initial version) WP1 - Management and coordination Read More D2.3 The iPROLEPSIS trustworthy AI framework WP2 - Knowledge mining, foundation and participatory design Read More D3.1 First report on PsA inflammation drivers research WP3 - Research on PsA inflammation drivers and monitoring Read More D4.4 The iPROLEPSIS serious gaming suite (alpha version) WP4 - Development of the iPROLEPSIS digital health ecosystem for personalised preventive care Read More D6.2 Dissemination, exploitation and communication plan WP6 - Dissemination, communication and exploitation Read More D6.8 Update on the Dissemination, Exploitation and Communication Plan WP6 - Dissemination, communication and exploitation Read More D2.1 Initial report on user research and co-creation process WP2 - Knowledge mining, foundation and participatory design Read More D2.4 Updated report on the state-of-the-art and datasets WP2 - Knowledge mining, foundation and participatory design Read More D3.2 First report on digital phenotyping for PsA WP3 - Research on PsA inflammation drivers and monitoring Read More D5.1 Study initiation package (iPROLEPSIS-PDPID study) WP5 - Clinical studies Read More D6.3 First report on project visibility and educational material WP6 - Dissemination, communication and exploitation Read More D2.2 Initial report on the state-of-the-art and datasets WP2 - Knowledge mining, foundation and participatory design Read More D2.5 Updated report on user research and co-creation process WP2 - Knowledge mining, foundation and participatory design Read More D4.2 The iPROLEPSIS patient and HCP apps (study version) WP4 - Development of the iPROLEPSIS digital health ecosystem for personalised preventive care Read More D6.1 Project branding and communication channels WP6 - Dissemination, communication and exploitation Read More D6.5 Midterm report on project visibility and educational material WP6 - Dissemination, communication and exploitation Read More

Learning how to live with psoriatic arthritis might feel like a challenge. But understanding your diagnosis can help you take control of your health. Learning Hub Explore resources to help you understand and manage psoriatic arthritis. Learning hub Key Facts Handbook News Feed Quizzes Search Psoriatic Arthritis Key Facts Key Facts Quizzes about Psoriatic Arthritis Take a Quiz Search about Psoriatic Arthritis Search Psoriatic Arthritis Handbook Handbook News Feed about Psoriatic Arthritis News Feed

< BACK iPROLEPSIS Lifestyle Recommendation Engine Co-Creation Insights Nov 12, 2024 User-Centered Development of the iPROLEPSIS Lifestyle Recommendation Engine The iPROLEPSIS project recently hosted its first co-creation session focused on refining the Lifestyle Recommendation Engine for individuals with Psoriatic Arthritis (PsA). This online session brought together a diverse, multidisciplinary group of 20 participants, including patient research partners from Portugal, The Netherlands, the UK, and Greece, along with clinicians, researchers, and developers from the iPROLEPSIS consortium. During the session, participants explored mockups and initial prototypes for nutrition and physical activity recommendations, offering valuable insights that guide iterative development towards a more user-centred and impactful design for the iPROLEPSIS Lifestyle Recommendation Engine. Purpose and Approach This collaborative effort aimed to improve the iPROLEPSIS Lifestyle Recommendation Engine, ensuring that it is user-centred and impactful. The session included detailed presentations of mockups and prototypes, followed by discussions where participants shared their perspectives and feedback on the nutrition and physical activity guidelines. Key Findings Strengths Clear Presentation: Participants appreciated the clarity of the nutrition and exercise recommendations, especially the structured breakdown of weekly meal plans and exercise intensity levels, which allowed for easy tailoring to user capabilities. User-Friendly Exercise Recommendations: Including exercise intensity was highly valued, helping users to select routines suitable to their abilities. Areas for Improvement Portion Sizes and Meal Timings : Participants recommended clearer definitions for portion sizes and specific guidance on meal timings to better support daily routines. Household Measurements : To improve accessibility, participants suggested including household measurements for ingredients, making recipes easier to follow. Cultural and Dietary Preferences : The inclusion of various cuisines, dietary options (e.g., vegetarian, gluten-free), and meal preparation cost considerations were recommended. Suggestions for Future Development Customizable Meal Plans : Participants supported options for users to create or choose from curated meal plans, along with suggested recipes for variety and personalisation. Enhanced Accessibility in Physical Activity : The need for exercise recommendations catering to different mobility levels was emphasised, with suggestions for low-intensity options for users with limited physical capacity. Safety Information and Usability : Feedback supported the inclusion of safety information for users with joint conditions and clarity enhancements in the app's design, particularly in colour-coding for specific goals. Interactive Goal Setting : Participants supported the inclusion of features for progress tracking and personalised goal setting to motivate users and enhance engagement. Participant Feedback and Satisfaction Participants expressed high satisfaction, particularly with the session’s structure and the collaborative nature of the discussion. Many appreciated the online format, which improved interaction. Looking Ahead The valuable feedback gathered will guide further development, ensuring the Lifestyle Recommendation Engine meets diverse user needs. Future iterations will aim to incorporate additional user-friendly features, making it easier for individuals with PsA to access personalised nutrition and physical activity recommendations tailored to their unique health goals and lifestyle preferences. 1/3 PREVIOUS NEXT

Learn more about international events for psoriatic arthritis. Choose the event and book the date. Upcoming and past events BIOSIGNALS at BIOSTEC 2027 May 14, 2027, 9:00 AM – May 16, 2027, 4:00 PM Nanjing, China More info LEARN MORE DSAI 2026 Jun 22, 2026, 9:00 AM – Jun 24, 2026, 4:00 PM Alexandroupolis, Greece More info Details iPROLEPSIS 8th Plenary meeting Jun 08, 2026, 10:00 AM – Jun 09, 2026, 5:00 PM Athens, Greece More info Details 60th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI) Jun 03, 2026, 9:00 AM – Jun 05, 2026, 4:00 PM Lisbon, Portugal More info Details Athens Digital Health Week 2026 Feb 16, 2026, 9:00 AM – Feb 20, 2026, 4:00 PM Athens, Athens, Greece More info Details iPROLEPSIS 7th Plenary meeting Dec 09, 2025, 9:00 AM – Dec 10, 2025, 4:00 PM Lisbon, Lisbon, Portugal More info Details IEEE HealthCom 2025 Oct 21, 2025, 9:00 AM – 7:30 PM Abu Dhabi, United Arab Emirates More info Details HLTH Event 2025 Oct 19, 2025, 9:00 AM – Oct 22, 2025, 6:00 PM Las Vegas, Las Vegas, NV, USA More info Details GRAPPA Annual Meeting 2025 Jul 10, 2025, 11:00 AM – Jul 12, 2025, 8:00 PM Bogota, Colombia More info Details iPROLEPSIS 6th Plenary meeting May 13, 2025, 11:00 AM – May 14, 2025, 5:00 PM Oxford, UK More info Details 7th Polythematic Panhellenic Congress of Autoimmune Diseases, Rheumatology and Clinical Immunology Mar 28, 2025, 10:00 AM – Mar 30, 2025, 8:00 PM Portaria, Pelion More info Details Health Data Summit 2025 Mar 19, 2025, 9:00 AM – Mar 20, 2025, 7:00 PM The EGG, Brussels, Belgium More info Details iPROLEPSIS 5th Plenary Meeting Dec 02, 2024, 7:00 AM – Dec 03, 2024, 5:00 PM Athens, Greece More info Details DSAI 2024 Nov 13, 2024, 7:00 AM – Nov 15, 2024, 5:00 PM Khalifa University, Abu Dhabi, United Arab Emirates (UAE) More info Details PhD Open Days 2024 - 10th edition Nov 05, 2024, 7:00 PM – 11:00 PM Lisbon, Portugal More info Details How to communicate about and disseminate project results under Horizon Europe Cluster 1 ‘Health’ and Horizon 2020 Oct 24, 2024, 12:00 PM – 1:00 PM GMT+3 Webinar More info Details 16th Panhellenic EPEMY Conference Oct 05, 2024, 8:00 AM – Oct 06, 2024, 6:00 PM Ioannina, Greece More info DETAILS Psoriatic Arthritis Awareness Day Sep 28, 2024, 8:00 AM – 11:50 PM Virtual More info DETAILS Load More

< BACK iPROLEPSIS Project Presented at HUMAN Lab Meetup Jul 15, 2024 Enhancing Learning Through Innovative Serious Games and Digital Interventions On 8 July 2024, the HUMAN Lab meetup was organised by Universidade de Lisboa (Instituto Superior Técnico, IST). During the event, Bárbara Ramalho and Hugo Escobar from FMH/IST-ULisboa presented the iPROLEPSIS project and the iPROLEPSIS Games. They discussed the project's main goals, motivations, and key milestones, providing insights into their roles in the design and development of serious games. The presentation also addressed the expected outcomes of the project, emphasising how these innovative tools are designed to enhance learning experiences and offer effective digital interventions. 1/3 PREVIOUS NEXT

< BACK iPROLEPSIS 5th Plenary Meeting in Athens Dec 5, 2024 Advancing the Development of Digital Solutions for Psoriatic Arthritis Care The iPROLEPSIS consortium gathered in Athens, Greece, on 2-3 December 2024, for the 5th Plenary Meeting. Hosted by Netcompany-Intrasoft and Wellics, this two-day event brought together consortium partners, the External Advisory Board (EAB), and the Project Officer (PO) to discuss key updates and map out the next steps in developing a personalised digital care ecosystem for people with Psoriatic Arthritis (PsA). The meeting focused on project updates, key achievements, and future plans for the Psoriatic Arthritis digital care ecosystem. Day 1 covered progress in the project, co-creation activities, and updates from various work packages. The team also demonstrated the iPROLEPSIS tools, including the miPROLEPSIS apps, HCP’s dashboard, and the Lifestyle Recommendation System. On Day 2, workshops were held on study designs, ecosystem development, and predictive models. Discussions also focused on data governance and dissemination strategies. 1/8 PREVIOUS NEXT