Learning Hub

< BACK iPROLEPSIS joins the YouTube channel Jan 23, 2024 Join Our Digital Journey – Follow iPROLEPSIS on YouTube iPROLEPSIS has officially joined the YouTube community . Follow our YouTube Channel: iPROLEPSIS - YouTube . Join us as we delve into novel digital solutions for psoriatic arthritis. Stay tuned for informative and engaging content! transparent-glass-bubble-with-youtube-logo-inside-it.jpg transparent-glass-bubble-with-youtube-logo-inside-it.jpg 1/1 PREVIOUS NEXT

< BACK iPROLEPSIS Games Presented at the Pitch Competition during PhD Open Days Nov 7, 2024 Showcasing iPROLEPSIS Games at the PhD Open Days Pitch Competition On November 5th, Bárbara Ramalho from FMH/IST-ULisboa had the opportunity to present the iPROLEPSIS Games at the Pitch Competition during the PhD Open Days event at the Técnico Innovation Center . In her pitch, Bárbara highlighted the role of serious games in the iPROLEPSIS project, which aims to improve the care and management of psoriatic arthritis (PsA) through a personalised, game-based digital ecosystem. The PhD Open Days gave over a thousand students the chance to connect, network, and showcase their research to the academic community, industry professionals, and alumni. The Pitch Competition was a great opportunity for researchers to present their work and meet potential collaborators. 1/5 PREVIOUS NEXT

< BACK iPROLEPSIS presented to Eli Lilly in the Netherlands Nov 8, 2023 Presentation to Eli Lilly introduces iPROLEPSIS as the next step in personalised psoriatic arthritis care On the 7th of November 2023, Ilja Tchetverikov from CICERO Rheumatology presented the results and prospects of the DEPAR cohort and introduced iPROLEPSIS clinical studies to the representatives of Eli Lilly company in the Netherlands. DEPAR, Dutch south-west Psoriatic Arthritis Registry, is a registry set up by Cicero Rheumatology, a partnership of rheumatologists working in 15 different hospitals in the south-west of the Netherlands. DEPAR, with the participation of well over 900 patients, supports rheumatologists to gain insight into the treatment and course of psoriatic arthritis. The presentation highlighted iPROLEPSIS as a logical next step in the further development of DEPAR, emphasising the project’s vision and aim to explain psoriatic arthritis inflammation through multi-source data analysis, guiding to a novel personalised digital care ecosystem. Slide1.JPG Slide2.JPG Slide6.JPG Slide1.JPG 1/6 PREVIOUS NEXT

< BACK iPROLEPSIS at Health Data Summit 2025 Feb 12, 2025 Trustworthy AI in Digital Health iPROLEPSIS is excited to join AI-PROGNOSIS and other Horizon Europe research and innovation projects - T RUSTroke, SmartCHANGE, and STRATIFYHF - at the Health Data Summit 2025 in Brussels. Together, these projects will focus on practical approaches for building trustworthy AI-enabled digital health tools aimed at assessing disease risk and progression. During the workshop titled " Trustworthy AI in Digital Health: From Guidelines to Practice" on 19-20 March 2025, iPROLEPSIS will join experts in discussing the importance of ensuring data quality, addressing bias, and applying ethical AI principles in healthcare solutions. The workshop will cover frameworks, methods, and techniques across the AI system development lifecycle, emphasising how to build AI tools that are robust, fair, transparent, and protect privacy. Key discussion topics include: Ensuring data quality and mitigating bias in AI-driven healthcare Applying ethical AI principles throughout AI system development Balancing fairness, privacy, transparency, and robustness The session will be an opportunity for iPROLEPSIS and its partners to contribute to advancing the responsible use of AI in healthcare and discuss solutions for improving digital health tools. Event details: Health Data Summit 2025 Programme details: Summit Programme 1/1 PREVIOUS NEXT

< BACK iPROLEPSIS Lifestyle Recommendation Engine Co-Creation Insights Nov 12, 2024 User-Centered Development of the iPROLEPSIS Lifestyle Recommendation Engine The iPROLEPSIS project recently hosted its first co-creation session focused on refining the Lifestyle Recommendation Engine for individuals with Psoriatic Arthritis (PsA). This online session brought together a diverse, multidisciplinary group of 20 participants, including patient research partners from Portugal, The Netherlands, the UK, and Greece, along with clinicians, researchers, and developers from the iPROLEPSIS consortium. During the session, participants explored mockups and initial prototypes for nutrition and physical activity recommendations, offering valuable insights that guide iterative development towards a more user-centred and impactful design for the iPROLEPSIS Lifestyle Recommendation Engine. Purpose and Approach This collaborative effort aimed to improve the iPROLEPSIS Lifestyle Recommendation Engine, ensuring that it is user-centred and impactful. The session included detailed presentations of mockups and prototypes, followed by discussions where participants shared their perspectives and feedback on the nutrition and physical activity guidelines. Key Findings Strengths Clear Presentation: Participants appreciated the clarity of the nutrition and exercise recommendations, especially the structured breakdown of weekly meal plans and exercise intensity levels, which allowed for easy tailoring to user capabilities. User-Friendly Exercise Recommendations: Including exercise intensity was highly valued, helping users to select routines suitable to their abilities. Areas for Improvement Portion Sizes and Meal Timings : Participants recommended clearer definitions for portion sizes and specific guidance on meal timings to better support daily routines. Household Measurements : To improve accessibility, participants suggested including household measurements for ingredients, making recipes easier to follow. Cultural and Dietary Preferences : The inclusion of various cuisines, dietary options (e.g., vegetarian, gluten-free), and meal preparation cost considerations were recommended. Suggestions for Future Development Customizable Meal Plans : Participants supported options for users to create or choose from curated meal plans, along with suggested recipes for variety and personalisation. Enhanced Accessibility in Physical Activity : The need for exercise recommendations catering to different mobility levels was emphasised, with suggestions for low-intensity options for users with limited physical capacity. Safety Information and Usability : Feedback supported the inclusion of safety information for users with joint conditions and clarity enhancements in the app's design, particularly in colour-coding for specific goals. Interactive Goal Setting : Participants supported the inclusion of features for progress tracking and personalised goal setting to motivate users and enhance engagement. Participant Feedback and Satisfaction Participants expressed high satisfaction, particularly with the session’s structure and the collaborative nature of the discussion. Many appreciated the online format, which improved interaction. Looking Ahead The valuable feedback gathered will guide further development, ensuring the Lifestyle Recommendation Engine meets diverse user needs. Future iterations will aim to incorporate additional user-friendly features, making it easier for individuals with PsA to access personalised nutrition and physical activity recommendations tailored to their unique health goals and lifestyle preferences. 1/3 PREVIOUS NEXT

< BACK iPROLEPSIS Plenary meeting Jun 22, 2023 iPROLEPSIS Consortium Partners Meet in Lisbon to Plan Next Steps The iPROLEPSIS consortium partners gathered in Lisbon, Portugal on June 20-21 for the 2nd Plenary meeting to review the progress and achievements of the project's work packages and plan the next steps. Over the course of two days, the consortium partners engaged in three productive workshops, each focusing on key aspects of the iPROLEPSIS project: Data Collection and Digital Biomarkers: The first workshop delved into the vital task of data collection and the development of digital biomarkers. Attendees discussed the identification of sensor and user data to be collected, including accelerometer/gyroscope data. Additionally, they explored algorithms for identifying inflammation drivers and defined user profiles to enhance personalized healthcare. System Architecture and Cloud Back-end: The second workshop centered around system architecture. The consortium partners discussed the key components of the system, including the orchestrator, and addressed critical aspects such as data management infrastructure and monitoring of app performance issues. miPROLEPSIS App and Serious Games: The third workshop involved a dynamic co-creation session, bringing together clinicians, patients, researchers, and developers. Focusing on the miPROLEPSIS app and serious games, participants explored various areas such as system architecture, key components, data management infrastructure, and app performance monitoring. The adoption of the "Crazy 8s" technique allowed for the rapid generation of a diverse range of ideas. During the third workshop patient representatives joined the session. Their valuable input and perspectives are crucial for understanding the specific needs and requirements of those who will benefit from our iPROLEPSIS project. By actively involving patient representatives, we can ensure that our solutions are truly patient-centric and tailored to their experiences and challenges. The iPROLEPSIS consortium is excited about the progress made during this meeting and is now equipped with a comprehensive plan for the next steps of the project. 3-1.jpg 3-1.jpg 1/1 PREVIOUS NEXT

< BACK "The Kite" Breathing Serious Game: Agile Co-Design for Psoriatic Arthritis Jul 31, 2024 Enhancing PsA Management through Innovative Breathing Exercises and Game-Based Therapy Latest research initiative under the iPROLEPSIS project: “The Kite” Breathing Serious Game: Agile Co-Design for Psoriatic Arthritis presented at IEEE MELECON 2024. This study is part of a broader effort to develop and validate innovative digital biomarkers for managing Psoriatic Arthritis (PsA) through the Artificial Intelligence-Personalised Game Suite (AI-PGS). Abstract: Serious Games (SGs) have the potential to provide clinical care and enhance patients’ quality of life, while incorporating an element of entertainment. As part of the iPROLEPSIS Horizon Europe project, we introduce two Sensorimotor Art games designed as SGs to assist Psoriatic Arthritis (PsA) patients in managing their symptoms. These SGs provide a platform for self-expression and pain relief through engaging in rhythmic puzzle activities. The co-design process for the proposed Sensorimotor Art games followed an agile methodology, involving 14 experts (including clinicians, researchers, and game developers), to gather feedback on game requirements, storyboards, and mechanics. From the thematic analysis of the transcribed discussion, four main themes emerged, namely: Clinical value (Theme 1), Motor skills and adaptation (Theme 2), Creative engagement (Theme 3), and Feedback and future directions (Theme 4). Clinical value underlines the therapeutic benefits of Sensorimotor Art games for pain distraction and emotional well-being. Motor skills and adaptation focus on hand/finger use and adapting games for older patients. Creative engagement emphasizes fostering creativity, a positive environment, and goal achievement. Finally, feedback and future directions highlight the importance of continuous feedback and occupational therapists’ involvement in coming sessions. The development of Sensorimotor Art games lays the groundwork for digital interventions to alleviate psychological distress and improve fine motor symptoms in PsA patients. At the same time, these SGs can also provide insights to healthcare providers and policymakers for developing future digital solutions tailored to PsA patients. Read the full publication: https://zenodo.org/records/13141465 IEEE_MELECON_2024 .pdf Download PDF • 1.33MB 1/1 PREVIOUS NEXT

< BACK Understanding Patient Perspectives on Digital Biomarkers for Psoriatic Arthritis Nov 28, 2024 A new study explores opportunities and challenges in using digital biomarkers for Psoriatic Arthritis management A recently published study, Digital biomarkers for psoriatic arthritis: a qualitative focus group study on patient-perceived opportunities and barriers , examines how patients with Psoriatic Arthritis (PsA) perceive the use of digital biomarkers (dBMs) in managing their condition. With the increasing use of wearables like smartphones and smartwatches, there is growing interest in utilizing these tools to track physiological and behavioral data in everyday life. This study, involving 27 PsA patients across six focus groups, sheds light on the potential benefits and limitations of integrating dBMs into PsA care. Key Insights The study identified three main areas of interest: Opportunities: Patients saw value in using digital biomarkers to track early signs of disease flare-ups and monitor symptoms over time. Disease Activity Mapping: Participants highlighted the importance of using a broad range of data points to reflect the complexity of PsA symptoms. Barriers: Concerns about privacy, data security, and maintaining strong connections with healthcare providers were key considerations for patients. Relevance to iPROLEPSIS The findings align with iPROLEPSIS’s goal of integrating patient-centered digital health tools into chronic disease management. This study offers important guidance on ensuring digital health innovations address real-world patient needs while maintaining trust and usability. e004699.full .pdf Download PDF • 1.55MB 1/1 PREVIOUS NEXT

< BACK iPROLEPSIS Sensorimotor Games Presented at DSAI 2024 Nov 20, 2024 Innovative digital games designed to support people with Psoriatic Arthritis presented at an international ICT conference. The iPROLEPSIS project coordinator, Prof. Leontios Hadjileontiadis, presented the iPROLEPSIS Sensorimotor Games at the 11th International Conference on Software Development and Technologies for Enhancing Accessibility and Fighting Info-exclusion (DSAI 2024) . The conference was held from 13–15 November at Khalifa University in Abu Dhabi, United Arab Emirates (UAE). The Sensorimotor Games are interactive digital applications designed for more than just entertainment. They combine enjoyment with skills training, social impact, and health improvement. As part of a personalised game suite, these games aim to support people living with Psoriatic Arthritis (PsA), offering a unique approach to enhancing their quality of life. DSAI is a leading international forum focused on accessible and usable Information and Communication Technologies (ICT). The conference provided an excellent platform to share progress on the iPROLEPSIS project and highlight its innovative approach to digital healthcare solutions. 1/2 PREVIOUS NEXT

< BACK Highlights from PETRA 2024 Jul 1, 2024 The iPROLEPSIS Exergames Introduced at PETRA 2024 The iPROLEPSIS Exergames were introduced and received very positively by the audience at PETRA 2024, a scientific interdisciplinary conference held on 26-28 June 2024 in Crete, Greece. Developing Exergames for Psoriatic Arthritis using Agile Storyboarding and Game Design Processes Abstract: Serious Games (SGs) offer significant potential in healthcare for disease assessment and intervention, enhancing patients’ quality of life. Exercise SGs, or Exergames, promote physical activity and mobility in a gamified environment, encouraging tailored exercises based on individual abilities and needs. Here, within the Horizon Europe iPROLEPSIS project that targets Psoriatic Arthritis (PsA), we describe the design process of Exergames to address PsA symptoms, including morning stiffness, impaired finger/hand and wrist functionality, and motor asymmetry. From a methodological point of view, the storyboarding technique was adopted to facilitate the visualization of the proposed Exergame scenarios, including the graphical user interface, interactive game elements, narratives, characters, and contexts related to the PsA condition. This approach has been implemented within an agile game development methodology, which includes gathering feedback early on to iteratively refine both the game ideas and prototype. Informed by the results of the game design via two agile sessions incorporating 25 participants (PsA patients, clinicians, technology developers, facilitators/observers), the current efforts are focused on developing the game prototypes and corresponding mock-ups, preparing them for upcoming clinical validation trials. The Exergames development lays the groundwork for an innovative framework to improve gross and fine motor symptoms in PsA patients. This framework could inform healthcare providers and policymakers about its potential inclusion in routine PsA management. Read the full publication: https://dl.acm.org/doi/10.1145/3652037.3663939 1/3 PREVIOUS NEXT

< BACK iPROLEPSIS Games Showcased at Lisboa Games Week 2025 Nov 24, 2025 The FMH/IST-ULisboa team presented the iPROLEPSIS Games, connecting with the gaming community and industry stakeholders The iPROLEPSIS Games were presented at Lisboa Games Week 2025 , held from 20–23 November in Portugal. The team from Faculdade de Motricidade Humana / Instituto Superior Técnico – ULisboa (Bárbara Ramalho, Samuel Gomes, Marta Vicente, Filipa Magalhães and Rodolfo Costa) showcased the serious games developed within the project. Lisboa Games Week is an event that reinforces the role of academic and professional training in the video game industry. Educational institutions present courses, projects, and programmes related to video game development, digital art, programming, design, animation, sound, virtual reality, artificial intelligence, and other technological and creative fields. The programme includes exhibitions, practical demonstrations, vocational guidance sessions, talks, and opportunities for direct contact with industry. Participation in this event provided a platform for presenting the iPROLEPSIS Games within a setting focused on education, creativity, and technological development. 🔗 https://lisboagamesweek.pt/ LGWPhoto4.jpeg LGWPhoto3.jpeg LGWPhoto3.jpeg LGWPhoto4.jpeg 1/4 PREVIOUS NEXT

< BACK iPROLEPSIS presented at the 2024 HIMSS European Health Conference Jun 11, 2024 Showcasing AI-Based Solutions for Psoriatic Arthritis Care Our project partner, PLUX Biosignals , participated in the 2024 HIMSS European Health Conference and Exhibition , where they showcased the innovative work of the iPROLEPSIS project, developing a novel personalised digital care ecosystem for people with psoriatic arthritis. The 2024 HIMSS European Health Conference and Exhibition was a major event for the European digital health community, bringing together approximately 2,500 healthcare executives, practitioners and professionals from 84 different countries in Rome. Held from May 29 to 31, the conference showcased the latest advancements in healthcare technology and provided a platform for critical discussions on the future of digital health in Europe and worldwide. HIMSS24 Europe addressed the region’s strategic initiatives in digital health, including the AI Act and the European Health Data Space, which aim to position Europe as a leader in digital health. HIMSS_iPROLEPSIS (2).jpg HIMSS_iPROLEPSIS (1).jpg HIMSS_iPROLEPSIS (2).jpg 1/2 PREVIOUS NEXT