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< BACK iPROLEPSIS Newsletter No. 5 Jul 10, 2024 Discover Insights from Clinicians, Collaborative Efforts, and Key Events Welcome to the fifth edition of the iPROLEPSIS project newsletter. In this issue, we bring you insightful interviews with clinicians specialising in psoriatic arthritis, insights into recent clustering and networking activities, and reflections on key past events. iPROLEPSIS_Newsletter No. 5 .pdf Download PDF • 8.01MB 1/1 PREVIOUS NEXT

< BACK European Researchers' Night Sep 30, 2024 Engaging Communities through Science Bárbara Ramalho, Hugo Escobar, and Marta Vicente from FMH/IST-ULisboa presented the iPROLEPSIS Games and the iPROLEPSIS project at the European Researchers' Night in Oeiras, Portugal. This event, part of the "Science for Everyone (SCIEVER) – Inclusion and Sustainability" initiative, aimed to engage the public with scientific advancements. Researchers from various fields participated, sharing their work through interactive presentations, live demonstrations, and diverse activities, fostering a stronger connection between science and the community. The event unerlined the importance of making scientific research accessible to all. 1/4 PREVIOUS NEXT

< BACK iPROLEPSIS Games Selected for HiTech 2025 Feb 13, 2025 Transforming Research into Real-World Solutions The iPROLEPSIS consortium partners from FMH/IST-ULisboa are pleased to announce that iPROLEPSIS Games has been selected as one of the 16 teams for the HiTech 2025 Program . HiTech 2025, organised by HiSeedTech , supports research teams in transforming deep tech innovations into market-ready solutions . This selection marks an exciting step forward for iPROLEPSIS Games , reinforcing our commitment to bridging the gap between scientific research and practical applications . 🔗 Read more about the program: HiSeedTech: Programs 1/1 PREVIOUS NEXT

< BACK iPROLEPSIS Presented at Health Data Summit 2025 Mar 27, 2025 Showcasing practical strategies for high-quality data mapping and harmonisation At Health Data Summit 2025 , organised by the European Institute for Innovation Through Health Data (i~HD) on March 18–19 in Brussels , the iPROLEPSIS project was presented by Thanos Vidakis from AINIGMA Technologies . The presentation was part of the session titled: "Advanced Strategies and Tools for Ensuring High-Quality Data During Data Mapping". It focused on how iPROLEPSIS uses the OMOP Common Data Model (CDM) and OHDSI tools to harmonize health datasets from various sources. By applying coding standards such as SNOMED , the project ensures consistency and interoperability across data systems. The talk also highlighted recent hands-on workshops with data experts , during which real-world data was mapped to the OMOP model and underwent quality checks . These steps are essential in delivering analytics-ready health data — a key goal of the project. iPROLEPSIS continues to support high standards in digital health research by promoting data quality, standardisation, and collaboration across partners. 1/2 PREVIOUS NEXT

< BACK iPROLEPSIS Games Pitch video from HiTech 2025 Jul 24, 2025 iPROLEPSIS Games presented during the HiSeedTech programme The iPROLEPSIS Games were presented at HiTech 2025 , a program by HiSeedTech. The pitch introduced the use of serious games to support treatment for Psoriatic Arthritis (PsA) , focusing on symptoms like mobility, pain, breathing, and emotional well-being. Watch the presentation here: HiTech 2025.png HiTech 2025.png 1/1 PREVIOUS NEXT

< BACK iPROLEPSIS presented at the 15th Portuguese Rheumatology Congress Oct 27, 2023 iPROLEPSIS project and iPROLEPSIS-PDPID study presented at the 15th Portuguese Rheumatology Congress On October 27, 2023, the Portuguese Society of Rheumatology (SPR) , a dedicated partner of iPROLEPSIS , took the stage at the 15th Portuguese Rheumatology Congress (XXV Congresso Português de Reumatologia) , the event attended by around 700 individuals, mainly rheumatologists and GPs. Cátia Gonçalves, Reuma.pt Study Coordinator, and Ana M. Rodrigues, Reuma.pt National Coordinator and Assistant Professor at NOVA Medical School, provided a comprehensive overview of the iPROLEPSIS project, its goals, and clinical studies. They also introduced the iPROLEPSIS-PDPID study , focusing on PsA digital phenotyping and inflammation drivers. Portuguese Rheumatology centres were invited to participate in the iPROLEPSIS-PDPID study, marking a significant step in advancing our research. News & Events iPROLEPSIS.png News & Events iPROLEPSIS.png 1/1 PREVIOUS NEXT

< BACK Federated Learning Aggregation based on Weight Distribution Analysis Oct 4, 2023 Enhancing Federated Learning: Leveraging Weight Distribution Analysis for Superior Aggregation Federated learning has recently been proposed as a solution to the problem of using private or sensitive data for training a central deep model, without exchanging the local data. In federated learning, local models are trained on the client side using the available data, while a server is responsible for aggregating the weights of these models into a global model. However, the traditional weight averaging approach does not take into consideration the importance of the different weights for the performance of a model. To this end, this work proposes a novel federated learning weight aggregation method that estimates the statistical distance of each client's parameters from the Gaussianity, and weighs the contribution of each client to the global model accordingly so that the most significant information is retained and enhanced. To create an accurate global model, a complex weighted averaging of the parameters of clients' models at the layer level is performed, considering as low quality the parameters following the Gaussian distribution. The proposed method can be employed to both convolutional and linear layers and it is based on the notion that parameters following a Gaussian distribution do not significantly affect the output of a model. Experiments with different network architectures and a comparison with a plethora of state-of-the-art approaches on three well-known image classification datasets demonstrate the superiority of the proposed method for federated learning weight aggregation. Read the full publication: https://www.researchgate.net/publication/374440973_Federated_Learning_Aggregation_based_on_Weight_Distribution_Analysis 1/1 PREVIOUS NEXT

< BACK British Society for Rheumatology Annual Conference 2024 Apr 26, 2024 Dr. Laura Coates Addresses Psoriasis to Psoriatic Arthritis Transition British Society for Rheumatology Annual Conference, the UK’s leading rheumatology event, took place on 24-26 April 2024. Dr Laura Coates discussed preventing the transition of psoriasis to psoriatic arthritis, including the evidence so far and studies underway with iPROLEPSIS and HIPPOCRATES IMI . Laura Coates_BRC 2024.jfif Laura Coates_BRC 2024.jfif 1/1 PREVIOUS NEXT

< BACK iPROLEPSIS Kick-Off Meeting Jan 8, 2023 iPROLEPSIS, a four-year Horizon Europe project on AI-enabled Psoriatic Arthritis screening, monitoring, and care, kicked off. iPROLEPSIS, a four-year H orizon Europe project on AI-enabled Psoriatic Arthritis screening, monitoring, and care, kicked off. Our consortium partners met in Thessaloniki, Greece, and during a two-day event laid the groundwork for this exciting research and innovation venture. The focus was placed on the four clinical studies that will be conducted in the project. News & Events iPROLEPSIS.png News & Events iPROLEPSIS.png 1/1 PREVIOUS NEXT

< BACK iPROLEPSIS 3rd Plenary meeting successfully closed Dec 14, 2023 Navigating Progress: Highlights from the 3rd iPROLEPSIS Plenary Meeting in Rotterdam On 12-13 December 2023 , the iPROLEPSIS consortium gathered for the 3rd plenary meeting in Rotterdam, the Netherlands. The agenda included: Four workshops External Advisory Board session Clinical studies overview, including PDPID study, Mast cells and optoacoustic-enabled joint and microvascular imaging (iPROLEPSIS-MOJMI) study, HPOS, and iPROLEPSIS integration General assembly session Overview of work packages with progress updates Strategic planning for the next steps. Four productive workshops were held: 1️⃣ PDPID study deployment and app: Ethical approval timeline SOP and OpenOpenClinica / eCRF App and cloud backend status UI/UX and translation timeline Usability testing 2️ ⃣ Digital biomarkers and data fusion Data retrieval roadmap Analysis methodologies Data fusion/modelling methodology MLOps solutions iPROLEPSIS-MOJMI-relevant biomarkers extraction 3️ ⃣ Technical workshop on digital ecosystem development Open issues and data collection monitoring Technical monitoring and orchestration needs MLOps technical aspects Alpha version of the digital ecosystem 4️ ⃣ Serious games co-creation session with patient partners Game design Stakeholders’ feedback We are grateful to patient representatives who joined the cocreation session . Their valuable input and perspectives are crucial for understanding the specific needs and requirements of those who will benefit from the iPROLEPSIS project. By actively involving patient representatives , we can ensure our solutions are patient-centric and tailored to their experiences and challenges. Thank you to Erasmus University Rotterdam for hosting the event. DSC03942.JPG IMG_7110.jpg iPROLEPSIS_cookies.JPG DSC03942.JPG 1/7 PREVIOUS NEXT

< BACK iPROLEPSIS Sensorimotor Games Presented at DSAI 2024 Nov 20, 2024 Innovative digital games designed to support people with Psoriatic Arthritis presented at an international ICT conference. The iPROLEPSIS project coordinator, Prof. Leontios Hadjileontiadis, presented the iPROLEPSIS Sensorimotor Games at the 11th International Conference on Software Development and Technologies for Enhancing Accessibility and Fighting Info-exclusion (DSAI 2024) . The conference was held from 13–15 November at Khalifa University in Abu Dhabi, United Arab Emirates (UAE). The Sensorimotor Games are interactive digital applications designed for more than just entertainment. They combine enjoyment with skills training, social impact, and health improvement. As part of a personalised game suite, these games aim to support people living with Psoriatic Arthritis (PsA), offering a unique approach to enhancing their quality of life. DSAI is a leading international forum focused on accessible and usable Information and Communication Technologies (ICT). The conference provided an excellent platform to share progress on the iPROLEPSIS project and highlight its innovative approach to digital healthcare solutions. 1/2 PREVIOUS NEXT

< BACK iPROLEPSIS 3rd Plenary Meeting Nov 30, 2023 iPROLEPSIS 3rd Plenary Meeting in Rotterdam: 12-13 December 2023 On 12-13 December 2023, iPROLEPSIS partners will meet in Rotterdam for the third plenary meeting. The agenda includes workshops on the PDPID study, digital biomarkers, technical ecosystem development, serious games co-creation, an External Advisory Board session, and more. Stay tuned for updates on our progress! iPROLEPSIS 3rd Plenary meeting (1).png iPROLEPSIS 3rd Plenary meeting (1).png 1/1 PREVIOUS NEXT